Thread by @Gas_Craic

Welcome to the @esicm webinar on renal issues in #COVID19 including AKI & CRRT esicm-tv.org #COVID19foam #foamed #FOAMcc

Low rates of AKI and CRRT initially thought. Does this marry up with the current picture?

AKI and CRRT data in #COVID19 currently. Real world data. #foamed #foamcc

Multiple, compounding mechanisms are seen to cause AKI in ARDS. Mediation via a pathway of inflammation, hypoxia and hypercapnia and it's associated sequelae (and of course MV!) #COVID19 #COVID19FOAM #FOAMed #FOAMcc

Are we seeing ferroptosis? Whereby DAMPs and inflammatory signally proliferates inflammation. #covid19 #foamed #FOAMcc

How do we explain variation in critically ill covid patients? There is possibly a six fold increased death rate in predominantly black countries. Is there a link with ACE polymorphism and SARS-CoV-2 susceptibility? #COVID19 #FOAMed #FOAMcc

RENAL: There is a significant resource issue with CRRT in #COVID19. The alternative is to consider intermittent RRT via a standard HD set or RRT set. Here are some broader considerations: #COVID19foam #foamcc #FOAMed

What does peritoneal dialysis look like as an alternative (resource-wise) to our usual CRRT modalities #COVID19 #FOAMed #FOAMcc

Protecting our CRRT circuits is a difficult job. They can suffer from clotting and protein caking. Here are some strategies for preventing their failure. Vascular access also important ++ #FOAMed #FOAMcc #COVID19

Consider your HD lines carefully #covid19 #COVID19foam #foamed #foamcc

Adjunctive strategies to attempt to prevent the creeping need for CRRT. Holistic care plays an important part of this. #COVID19 #foamed #FOAMcc

Is there a role for cytokine removal/blood purification in #COVID19? #FOAMed #FOAMcc

Dynamic and evolving area of work. No universal plan. Adaptive strategies. Less than ideal circumstances. Team work essential. #COVID19 #foamed #FOAMcc