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⚠️𝐌𝐢𝐜𝐫𝐨𝐂𝐋𝐎𝐓𝐒 nuevo nombre para el SDRA severo/crítico en #COVID__19 #COVID19🤔🤯

🇮🇹700 pacientes con ARDS severo
>100 paciente en UCI
1️⃣🦠 daña el alveolo
2️⃣Reacción inflamatoria
🚨 TROMBOSIS pulmonar MICROVASCULAR⚠️
FMO &☠️🔚

bit.ly/2VlzKnL
🧵👇🏻
Se ha atribuido el daño a la 𝐭𝐨𝐫𝐦𝐞𝐧𝐭𝐚 𝐝𝐞 𝐜𝐢𝐭𝐨𝐜𝐢𝐧𝐚𝐬

🆙Pero, la 𝐜𝐚𝐬𝐜𝐚𝐝𝐚 𝐝𝐞𝐥 𝐜𝐨𝐦𝐩𝐥𝐞𝐦𝐞𝐧𝐭𝐨 intensificaría la respuesta inmune

↪️Masivo daño del endotelio vascular y del epitelio alveolar

🚨🆕Trombosis microvascular⚠️💔
bit.ly/2XNntdf
La evolución del ARDS
•Empeoramiento de la V/Q
•Pérdida del reflejo de vasoconstricción por hipoxia
🚨Marcada trombosis pulmonar microvascular

Datos de 🇫🇷
17% trombosis pulmonar a pesar de ACO profilaxis o terapéutica
Sin necesidad de presentar CDI

bit.ly/3ezvYP9
En 1998 estos hallazgos fueron descriptos en pacientes con SDRA severos.

Sin embargo fue relacionado con la etiología post-traumática y no con la severidad.

bit.ly/3boDtX7
No hay que ovidarse de los efectos tromboticos en el ❤️

El daño miocárdico está presente
👥30% desarrolla miocardiopatía en UCI

🚨SIRS e inflamación localizada de la placa/vascular

No todos los SCA se deben a eventos trombóticos...... IAM tipo I

bit.ly/3amgF9d
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