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Crushing the Curve, aka Squashing:
I've been posting on the successful countries countering #COVID19.
Today good to see recognition for New Zealand, Australia and Vietnam
🇳🇿🇦🇺
nytimes.com/2020/04/24/wor… by @damiencave A1 @nytimes
🇻🇳
wsj.com/articles/some-…
by @NiharikaSM @LamLe52
15 countries that went horizontal
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Eric Topol
@EricTopol
Today there's a buzz about children w/ #COVID19 not transmitting to adults. It's wrong.
bloomberg.com/news/articles/… @bloomberg by @abdroma @DFTBubbles and
economist.com/international/… @TheEconomist
Cases have indeed been documented and kid's viral load is similar
"Uncommon"(@ECDC_EU) yes. Not super-spreaders, yes. Unheard of, no. Many kids are asymptomatic carriers, same viral load as adults.
It would be naive to say it doesn't happen when it is woefully understudied ("Absence of evidence...")+ there is ample evidence
from @TheEconomist
The Chinese in-depth contact tracing study @ScienceMagazine in the thread above, that I posted about yesterday, showed that children have reduced ability to transmit, ~70%. That isn't zero, by any means. And it's still very much understudied. science.sciencemag.org/content/early/…
Read 3 tweets
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Eric Topol
@EricTopol
If the US did 100 million #COVID19 tests today, it would still not be the best country in the world for testing, as wrongly asserted every day by @POTUS. It will never be. It essentially didn't do any tests for 2 months after its 1st patient. Timing is everything.
More on this topic, since too many people still don't understand its vital importance, from @MaxCRoser @OurWorldInData
It doesn't matter much how many tests are done now, after the spread and damamge is done
You can see all the countries #COVID19 testing as a function of WHEN they started and per 1000 people, from this new, terrific graph @OurWorldInData by @MaxCRoser @EOrtizOspina @JoeHasell @UniofOxford
ourworldindata.org/grapher/total-…
Read 5 tweets
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Eric Topol
@EricTopol
The new remdesivir data from Tony Fauci from N >1,000 placebo-controlled trial (unpublished, Oval Office citation) does not show statistically significant reduction in mortality (8% vs 11%, in the right direction) but a clear-cut benefit in time to recovery 11 vs 15 days, P<0.001
It's been a very confusing story. First a positive signal from compassionate use @NEJM, then @UCHicagoMed leak encouraging. Then @Lancet today clearly negative trial, underpowered. Then this.
The good news: it looks like we now have a drug w/ some efficacy. And that's very good.
I'm feeling better that the signal I called weeks ago from the 1st report panned out to be true, despite many who challenged the call
Read 6 tweets

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