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Stop saying that higher protein intakes cause renal failure, you are wrong. From the WHO/FAO:
“…the suggestion that the decline of glomerular filtration rate that occurs with advancing age in healthy subjects can be attenuated by reducing the protein content
in the diet has no foundation.”
From the IOM in setting the last DRI:
“…protein content of diet is not related to progressive decline in kidney function with age.”

A causal link? No evidence:
Changes in Kidney Function Do Not Differ between Healthy Adults Consuming
Higher- Compared with Lower- or Normal-Protein Diets: A Systematic Review and Meta-Analysis
academic.oup.com/jn/article/148…
A Systematic Review of Renal Health in Healthy Individuals Associated with Protein Intake above the US Recommended
Daily Allowance in Randomized Controlled Trials and Observational Studies academic.oup.com/advances/artic…

#RDchat #protein #aging #sarcopenia
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mackinprof
@mackinprof
So it's playing out like this. Build up your muscle, stay fit; it's our reserve against a catabolic episode (1). When you relax and put your feet up, things go south (fast) and take, it appears, a long-time to recover (2).
Now this pandemic has provided a blanket catabolic episode for lots of people, and the age demographics and poor metabolic health of folks don't bode well (3). People can say it 'only' kills older people and those with pre-existing conditions, but who in NA is healthy anymore?
Lack of sleep, poor nutrition, lack of exercise, cancer is prevalent, plus exposure to a test of immunity and resilience equals a poor outcome? Likely never been a time, and hopefully, there will never be another time when the message of building resilience to a catabolic threat
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Stuart Phillips
@mackinprof
From the @ThePhySoc 2016 Biomedical Basis of Elite Performance conference 25min to pass some time: muscle protein turnover and hypertrophy. Some reading that is now almost 4 years ahead to support the points made:
1) Protein helps to augment hypertrophy
but its influence is quite small pubmed.ncbi.nlm.nih.gov/28698222 - @RobMorton23 as the main protagonist.

2) High loads are not required for hypertrophy, or for a large part strength gains (especially if one 'practices' lifting heavy loads) pubmed.ncbi.nlm.nih.gov/28834797 - @BradSchoenfeld
as the main protagonist on this meta-analysis and some of our work on this - pubmed.ncbi.nlm.nih.gov/20711498 (read first), pubmed.ncbi.nlm.nih.gov/22518835 (read second), and pubmed.ncbi.nlm.nih.gov/27174923 (read third).

3) The acute rise in systemic 'anabolic' hormones plays little, if any, role
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