Thread by @IRBBarcelona

Researchers from the @bbglab at @IRBBarcelona have contributed to the discovery of #LesionSegregation, explaining how DNA damage caused by chemical mutagens is not repaired immediately and can create more genetic diversity in tumours.
➡️bit.ly/2Nv8u1c
by: @emblebi
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The work has been published in the journal @nature.
“This process, which we named #lesionsegregation, is very revealing to understand how mutations occur, a key step in the evolution of cancer,” says @nlbigas.
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“Persistent DNA lesions induced by chemotherapeutic agents segregate and produce several generations of further mutations. We need to be aware of this therapeutically, and in future drug development," explains @mst_paralogue from @EdinburghUni.
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The discovery has been developed in the context of the @LCE_Consortium. “This work is a great example of collaborative science, where scientists with different fields of expertise in biology work together to move science further,” says @oriol_pich.
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And... Don't miss this #tweetorial by @S_J_Aitken from @CRUK_CI, first author of the paper, to get a quick overview!

https://twitter.com/S_J_Aitken/status/1275813913196707841?s=20

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@S_J_Aitken @CRUK_CI 📢Also, don't miss this interview with @oriol_pich, Medical Doctor, MBA and PhD student at the @bbglab (@IRBBarcelona) who participated in the study.

Learn more about his latest research projects, PhD life and future plans! ➡️bit.ly/31cAGy5
#WeAreIRB