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1) With #BottleofLies just out in paperback, I wanted to revisit its key disclosures, the book's impact and explore: has our fraud-fueled drug-quality crisis changed for better or worse? @eccobooks @AltFda Thread 👇
2) #BottleofLies recounts wild fraud at India's largest Rx co. Ranbaxy, maker of low-cost meds 4 US patients including 1st version of generic Lipitor (which contained glass particles/pic below). Ranbaxy would be operating today had @D_S_Thakur not risked his life to expose truth.
3) Ranbaxy's fraud was encapsulated in a smoking-gun internal PPT shown to company directors: the company had registered over 200 products in more than 40 countries using fake data. For 1st time, I am making the full doc available here: katherineeban.com/new-page @PeterAttiaMD
4) Despite industry claims to contrary, manipulation of data at generic Rx plants overseas is ongoing, w/ plants concealing records in scrapyard, smuggling them out of plants before @US_FDA arrives - all to get failing drugs approved: buff.ly/331n2vT
5) Since #BottleofLies came out, I have been deluged w/ Qs from readers, aghast that they lack basic information about where their drugs come from or whether they're safe. So I put together this Guide to Investigating Your Own Drugs: katherineeban.com/guide
6) In the last year, Congress has focused intently on the problem #BottleofLies exposed: ineffectual, pre-announced FDA inspections overseas, with foreign manufacturing plants serving as hosts and travel agents for FDA investigators. Here's what it looked like:
7) Remarkably, at a recent @SenFinance hearing, FDA Associate Commish Mark Abdoo testified, as though it were a sufficient reform: "We stopped having firms make our hotel selections for us." Here's the clip. @EnergyCommerce @SenateFinance
8) The #coronavirus pandemic has laid bare the perils of our dependence on an overseas drug supply. The FDA suspended foreign inspections, relying only on company data; it turned to uninspected and subpar factories overseas to make drugs in short supply: reut.rs/2Z0c88M
9) A movement is building to "reshore" the manufacturing of our lifesaving drugs, to make them on U.S. soil using a not-for-profit model: nbcnews.to/3g0Y7i9 But that alone is not enough. @PeterKolchinsky
10) Patients deserve basic transparency and verified quality. I lay out the crisis and a call for needed change in this recently-posted 16-min @TEDMED talk, here: tedmed.com/talks/show?id=…
11) “Eban’s tale of deception and intrigue unfolds like a thriller," as one recent reviewer described it. You can pick up a copy of the paperback, with a new postscript, here: amzn.to/3fZugpZ @CarnegieCorp
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