Thread by @dockaurG

53+ published #HCQ studies in #COVID19—strong efficacy as prophylaxis & as treatment in early COVID19. HCQ is std of care in COVID19 tx protocols for many countries🌎 w/lowest fatality rates. Govts allowing ppl to die by blocking access to life-saving meds
c19study.com

2/#HCQ activates host anti-viral innate immunity—strong efficacy as prophylaxis & as treatment in EARLY #COVID19 esp w/in 5d of symptoms. Now we know why

CDC: >88% don't yield replication-competent #SARSCoV2 virus after 10d & viral shedding drops after 6d
cdc.gov/coronavirus/20…

3/ Recent pre-print systematic review & meta-analysis on "#SARSCoV2 viral load dynamics, duration of viral shedding & infectiousness" found:
"SARSCoV2 titres detectable in first week of illness with early peak observed at symptom onset to day 5 of illness"
medrxiv.org/content/10.110…

4/HCQ ineffective when used in
-toxic doses
-wrong patient population
-wrong time of disease

Published studies show #HCQ effective when approp doses used either as pre-exposure prophylaxis or as treatment w/in 5d of symptom-onset esp in high-risk patients

https://twitter.com/JamesTodaroMD/status/1289563464499781632

https://t.co/JwqzjW7g8R

5/ Critical to understand:
early COVID19 & late COVID19 are distinctly different. #HCQ effective as an anti-viral in EARLY COVID19.

HCQ doesn’t work in late #COVID19. Hyperactive immune response leading to a “cytokine storm” often occurs in late COVID19.
frontiersin.org/articles/10.33…