1/
I want to thank all my colleagues for the wonderful #COVID19 research they published during these months: >200 PubMed-indexed articles from @SanRaffaeleMI @SRAnesthesiaICU @MyUniSR @azangrillo
I’ll summarize few of them in this thread.
I want to thank all my colleagues for the wonderful #COVID19 research they published during these months: >200 PubMed-indexed articles from @SanRaffaeleMI @SRAnesthesiaICU @MyUniSR @azangrillo
I’ll summarize few of them in this thread.
2/
In February, before the start of #COVID19 in Europe, we suggested the use of helmet to deliver #CPAP #NIV in emergency departments. This can be a key issue to prevent future spread of respiratory pandemics in emergency departments.
thelancet.com/journals/lance…
In February, before the start of #COVID19 in Europe, we suggested the use of helmet to deliver #CPAP #NIV in emergency departments. This can be a key issue to prevent future spread of respiratory pandemics in emergency departments.
thelancet.com/journals/lance…
3/
As soon as #COVID19 spread in Lombardy we helped other centers to manage their worst patients: 39 patients from other centers were admitted in our ICUs. The H was reshaped to cope with the new situation. The manusc cited 38 times in the first 4 months.
As soon as #COVID19 spread in Lombardy we helped other centers to manage their worst patients: 39 patients from other centers were admitted in our ICUs. The H was reshaped to cope with the new situation. The manusc cited 38 times in the first 4 months.
4/
We gave to #COVID19 disease a new name: #microCLOTS and underlined the importance of inflammation and thrombosis in research and in treatment strategies. This manuscript was cited 78 times in the first 4 months.
We gave to #COVID19 disease a new name: #microCLOTS and underlined the importance of inflammation and thrombosis in research and in treatment strategies. This manuscript was cited 78 times in the first 4 months.
5/
We published the first case series of western ARDS invasively ventilated #COVID19 patients suggesting that short term mortality was relevant but not so high as previously reported in Chinese cohorts... and several other hints
We published the first case series of western ARDS invasively ventilated #COVID19 patients suggesting that short term mortality was relevant but not so high as previously reported in Chinese cohorts... and several other hints
6/
We were the first ones to administer the vasoconstrictor angiotensin II in #COVID19 patients and to share the findings.
We were the first ones to administer the vasoconstrictor angiotensin II in #COVID19 patients and to share the findings.
8/
We were the first ones to report the beneficial effects of the immunosuppressant anakinra in hyperinflammed #COVID19 ARDS patients to reduce invasive ventilation/mortality. (already cited 93 times in 3 months)
We were the first ones to report the beneficial effects of the immunosuppressant anakinra in hyperinflammed #COVID19 ARDS patients to reduce invasive ventilation/mortality. (already cited 93 times in 3 months)
9/
We confirmed that tocilizumab has anti-inflammatory properties in #COVID19 patients, but that its widespread use is not indicated so far.
We confirmed that tocilizumab has anti-inflammatory properties in #COVID19 patients, but that its widespread use is not indicated so far.
10/
We also tested #mavrilumumab and #sarilumab in hyperinflammed #COVID19 ARDS patients outside the ICU.
ard.bmj.com/content/early/…
We also tested #mavrilumumab and #sarilumab in hyperinflammed #COVID19 ARDS patients outside the ICU.
ard.bmj.com/content/early/…
11/
We reported the rate of AKI/RRT in #COVID19 invasively ventilated patients and the outcome of patients with this complication.
We reported the rate of AKI/RRT in #COVID19 invasively ventilated patients and the outcome of patients with this complication.
12/
We identified older age, coronary artery disease, cancer, low lymphocyte count and high RALE score as predictors of poor outcome in a large cohort of hospitalized #COVID19 patients.
We identified older age, coronary artery disease, cancer, low lymphocyte count and high RALE score as predictors of poor outcome in a large cohort of hospitalized #COVID19 patients.
13/
We reported the counterintuitive protective effect of active smoking on the progression of #COVID19 disease in our hospital and worldwide
We reported the counterintuitive protective effect of active smoking on the progression of #COVID19 disease in our hospital and worldwide
14/
We demonstrated that the use of home ventilators designed for support of patients with sleep apnoea and/or chronic respiratory insufficiency is feasible in ARDS #COVID19 patients.
We demonstrated that the use of home ventilators designed for support of patients with sleep apnoea and/or chronic respiratory insufficiency is feasible in ARDS #COVID19 patients.
15/
We were the first ones to publish an important reduction in 30 days mortality in hospitalized #COVID19 patients over time
We were the first ones to publish an important reduction in 30 days mortality in hospitalized #COVID19 patients over time
