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Giovanni Landoni, MD Profile picture
Giovanni Landoni, MD
@giovannilandoni
Full Professor, Anesthesia and Intensive Care Medicine Residency Program Director @MyUniSR @SanRaffaeleMI
Feb 10, 2023 • 4 tweets • 3 min read
1/
 Is it ethical to interrupt a #RCT early because the treatment group is doing too well?

In my opinion NO

Here is a practical example 2/
 Adding #pyridostigmine to standard care reduced mortality among patients hospitalized for severe #COVID19

in Mexico a small study of 94 patients per group performed in hospitalized, severe (on oxygen, but not intubated) #covid19 patients

molmed.biomedcentral.com/articles/10.11…
Jan 1, 2023 • 5 tweets • 5 min read
in 1932 #oxygen was delivered subcutaneously!
with non-negligible success

#ARDS #ecmo
1/
physoc.onlinelibrary.wiley.com/doi/epdf/10.11… In 1933 #oxygen wad delivered through the peritoneal cavity and stomach
with non-negligible success

#ARDS #ecmo
2/
physoc.onlinelibrary.wiley.com/doi/pdf/10.111…
Jun 12, 2021 • 7 tweets • 3 min read
We identified all sudden cardiac death occurring in Italian youngster (1-35y) and reported by media 2010-2015 under the leadership of @sozi81
pubmed.ncbi.nlm.nih.gov/33638776/
#Eriksen @IntensiveBot
1/ Image Autopsy data were available in 100/132 (75.8%) cases: an extra cardiac cause was identified in 20 (20%). Among the 61 cases with a cardiac diagnosis, 21 (34%) had hypertrophic cardiomyopathy.
2/
Jul 27, 2020 • 19 tweets • 24 min read
1/
 I want to thank all my colleagues for the wonderful #COVID19 research they published during these months: >200 PubMed-indexed articles from @SanRaffaeleMI @SRAnesthesiaICU @MyUniSR @azangrillo
I’ll summarize few of them in this thread. 2/
 In February, before the start of #COVID19 in Europe, we suggested the use of helmet to deliver #CPAP #NIV in emergency departments. This can be a key issue to prevent future spread of respiratory pandemics in emergency departments.
thelancet.com/journals/lance…