@angryhacademic Seeking long term studies of ACM/MM of #LCHF diets asks the wrong question, and wouldn't likely ever be done anyway. What would the control arm be, and how would you ever isolate just a single dietary (macro?) difference? The question to ask is given someone is not healthy as 1/
@angryhacademic are 80%+ of the adult population (e.g., poor bio-markers, low QoL measures, presence of multiple chronic disease dx), do they improve on #LCHF/#ZC intervention? That does happen. As an aside, there are some longer term carnivores around who despite consuming no fiber, fruits, 2/
@angryhacademic veg for many years are thriving—no signs of survey or GI problems. The evidence is out there if you look for it. But since this would never be a pharmaCo drug intervention, there wouldn't be an RCT because there's no money in it. Last, I don't think many claim ↑LDL is 3/
@angryhacademic healthy, but suggest it's not unhealthy given a LCHF diet, as many cholesterol/lipid hypothesis proponents, lipidologists, and statin advocates believe. You'll find chronic hyperglycemia and hyperinsulinemia much more ASCVD and ACM causative than elevated LDL, even in FH. /fin
