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(1/3) A new pre-print study (interpret cautiously) sheds light on how #SARSCoV2 might damage the heart.

Attempting to achieve herd immunity without a vaccine is a grave error.

Press release:
biospace.com/article/releas…

Study:
biorxiv.org/content/10.110…
(2/3) In the study, researchers exposed human heart cells to #SARSCoV2 in a laboratory, and observed highly unusual changes.

They then compared the laboratory findings to heart tissue obtained from 3 deceased #COVID19 patients and found similar changes.
(3/3) It is unclear if such changes are common.

However, heart abnormalities have been detected in patients who experienced moderate #COVID19.

These abnormalities might predispose to heart disease later in life.
sciencedirect.com/science/articl…
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Dr Zoë Hyde
@DrZoeHyde
(1/5) Study of 91 children with #COVID19 from South Korea, showing that symptom screening will fail to identify the majority of cases in children, and that viral RNA can be detected for an unexpectedly long time.
jamanetwork.com/journals/jamap… Image
(2/5) Children were tested if they had a history of close contact with a known case, had an epidemiological link to an outbreak, had arrived from abroad, or had symptoms suggestive of #COVID19. This means the study is likely representative, as few cases are missed in South Korea.
(3/5) Approximately one-fifth of children (22%) were asymptomatic.

Of the children who were symptomatic, 66% had symptoms which went unrecognised before they were tested.

Only 6 children (9%) were diagnosed at the time of symptom onset.
Read 5 tweets
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Dr Zoë Hyde
@DrZoeHyde
(1/22) Study of household transmission of #SARSCoV2 in the US in March to April. Extremely thorough investigation by the CDC showing an equal attack rate for children and adults, among other things. Lots to discuss here... #COVID19
doi.org/10.1093/cid/ci…
(2/22) The investigation took place in Utah and Wisconsin. These states were chosen because of the low #COVID19 prevalence at the time, reducing the risk of additional exposure to household members.
(3/22) Index patients were identified via outpatient testing. After this, a list of households to which index patients belonged was established.
Read 22 tweets
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Dr Zoë Hyde
@DrZoeHyde
(1/15) Study describing a probable case of #SARSCoV2 transmission by an asymptomatic person (completely without symptoms during infection) on an aeroplane during an evacuation flight to South Korea. #COVID19
wwwnc.cdc.gov/eid/article/26…
(2/15) This study included 310 people who boarded an evacuation flight from Italy to South Korea in March. Before boarding, 11 symptomatic people were identified, and removed from the flight.
(3/15) The remaining 299 people boarded. They were issued with N95 respirators, and sat 2m apart. Most passengers wore the N95 masks, except at mealtimes and when using the toilet.
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