"We'd like to see a vaccine with at least 50% efficacy preferably higher”, says @doctorsoumya. Ideally lower bound off efficacy would not be below 30%.
If vaccine is approved prematurely, risk is:
1. will be make it difficult to continue randomised trials
2. vaccine could have low efficacy or be harmful
Bruce Aylward says EU is joining forces with COVAX, as well as individual countries like Germany. “So far it looks quite encouraging”, he says.
“While we don't have a complete picture of what transmission looks like within children there appear to be differences by age group”, says @mvankerkhove. "So we're still learning."
"I think what we're finding out is that our new normal includes physical distancing, our new normal includes making some modifications to our daily life to keep ourselves protected” and to protect others, says @mvankerkhove.
@mvankerkhove explains that a PCR detects viral fragments, but a positive test does not necessarily mean someone is infectious. Tests looking to isolate live virus give a better sense of that.
“Our preferred approach is to have complete data sets that could be used for pre-qualification of vaccines, and that would then allow large scale procurement by global bodies”, says @doctorsoumya.
“There is a misunderstanding that Sweden has not implemented control measures", says @DrMikeRyan. "Sweden has implemented quite strong control measures for COVID."
"I've seen some very creative nightclub situations where ... you'd only have one or two people per car, and no one can leave their car and there's a DJ playing", says @mvankerkhove. "We are social creatures."
“It's really important that governments don't overreact to people protesting against measures”, says @DrMikeRyan. Important to enter into a dialogue. "And you may not convince everybody."