The tragedy is how predictable this has been since at least early July. It was not inevitable. It is not inevitable now that this worsens, but to avoid spiralling out of control needs to be action now. We are close to or at events & choices of 13-23 March. theguardian.com/world/2020/oct…
More data always useful, but don't try & bring more precision to public health interventions than a highly complex system allows. If strategy is to reduce r<1, transmission, hospitalisations,deaths,pressure NHS directly & indirectly it will need package of interventions now.
We are back to choices faced in the early March. With the lag time between making a decision, its implementation & its effect measured in weeks the longer the decisions are delayed the harder & more draconian are the interventions needed to change trajectory of epidemic curve.
Don't act slower than the speed of the epidemic, don't get behind an epidemic curve. So much harder to turn that epidemic curve around.
Every day that a decision is delayed or deferred is a decision in itself & in the fast moving dynamic phase of an epidemic any delay has its own consequences.
• • •
Missing some Tweet in this thread? You can try to
force a refresh
Plan Continuation bias (PCB) - playing a role in COVID19? Lessons from aviation industry. A fancy name for “get-there-itis”. PCB which is an unconscious cognitive bias to continue the original plan in spite of changing conditions — & it can be deadly for general aviation pilots
Plan continuation bias was identified in a NASA Ames human factors study from 2004 which analyzed 19 airline accidents from 1991 to 2000 that were attributed to crew error. Out of those, almost half involved plan continuation bias. humansystems.arc.nasa.gov/flightcognitio…
Problem is in how it manifests. Study offered it becomes stronger as you near completion of the activity (e.g., approach your destination). It essentially impedes pilots from recognizing that they need to change course of action & because it’s unconscious,it often goes undetected
Latest data-COVID UK.Tough political decisions to be made. But data is clear. Community transmission increasing. Number people needing hospitalisation increasing. Tragically more people dying. Options for interventions might be debated but data is clear. theguardian.com/uk
UK is on an epidemic path. The epidemic will continue to expand under the current restrictions. A choice we face. Need to be honest about the implications for the choices that are made. wellcome.org/news/covid-19-…
Great pleasure to join the @isirvAVG Therapeutics Meeting.
Thank you to Alan Hay & Fred Hayden & Organising Committee. isirv.org/site/images/co…
1) Critical need for therapeutics for COVID19 in prevention, treatment & to halt progression of illness. Understandable focus globally on vaccines but even when we have vaccines we will still need therapeutics (& Diagnostics & Health Systems to make them available).
Always good to remember that for many infectious diseases we do not have vaccines despite many years of great effort & we know therapeutics can play critical role in reducing transmission, burden disease & save lives - HIV, TB, Malaria, Dengue & many others.
Tomorrow's @thesundaytimes. Data is clear. Political & societal decisions on what to do extraordinary difficult. Very little room for a middle way that keeps things open & also prevents transmission, illness & COVID/NonCOVID deaths. Needs a national debate thetimes.co.uk/article/no-fud…
Not possible keep society & economy open as now & suppress transmission,prevent hospitalisations & deaths COVID & non-COVID & pressure on NHS. Anyone suggesting there are easy political decisions or possible to open society & economy & control epidemic is doing a great disservice
Need urgent national debate & political decisions to be made & fairly binary choice:Open up society & economy but accept higher transmission,hospitalisations & deaths vs further restrictions implemented now, reduce transmission, keep schools open & reduce COVID illnesses & deaths
The ability to control the initial infection through type I IFN may be so important in COVID and also many other acute viral infections - Flu, Dengue, Yellow Fever, Chik, and others.
Idea that these infections are characterised by inability to control initial infection. As a result of a poor early immune response. Followed later by an exaggerated & uncontrolled response.
Absolutely right UK as Europe at tipping point. Tipping points not defined by a day they happen over wks as transmission increases. Later functional interventions in place harder & longer they are needed to reduce transmission.Very tough political choices independent.co.uk/news/uk/politi…
No easy, simple non-disruptive choices. It is simply not possible to have everything open, working, schools/HE/FE back & also reduce transmission & prevent all COVID related and unrelated illness. These are very hard political choices & none are easy.
A "Swedish" model is not that different. Anyone offering simple, easy options, or arguing that everything can be opened up without restrictions & such a choice will have little or no consequence is doing a disservice to society & to the choices that need to be made.