⚠️BREAKING—huge SOLIDARITY randomized trial by @WHO shows that the drug Remdesivir had **no effect** on reducing #COVID19 mortality at 28 days. The widely touted & hyped drug taken by Trump, also did *NOT prevent initiation of ventilation*, *nor shorten hospital stay*. Nothing!
2) and they indeed checked subgroups. and did a meta analysis pooling. Still nothing burger 🍔 for remdesivir. medrxiv.org/content/10.110…
➡️ THIS IS WHY WE DO TRIALS FOLKS!!!
3) Also this wasn’t a tiny study. It was done in 405 hospitals worldwide 🌎 in 30 countries—11,266 adults were randomized, w/ 2750 allocated Remdesivir, 954 Hydroxychloroquine, 1411 Lopinavir, 651 Interferon plus Lopinavir, 1412 only Interferon, & 4088 no study drug.
EPIC size.
4) Also it was a #Hydroxychloroquine trial too! And guess what? NOTHING either for mortality. In fact, HCQ treated patients were trending in worse direction, opposite of any benefit. HCQ is basically dead at this point. Folks, trials matter! #COVID19
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📍ATLAS SHRUGGED & PEOPLE DIED. Trump’s WH pandemic advisor Scott Atlas arm-twisted CDC to say no need to test asymptomatic people for #COVID19 *even if exposed to virus*—angering Drs. Birx & Redfield. Atlas now tied with Miller for worst Trump advisor. 🧵nytimes.com/2020/10/16/bus…
2) “Many public health experts say that a far more sweeping program would save lives and bolster the economy by helping as many Americans as possible learn quickly if they are infected. Atlas and other WH officials virus response effectively say the opposite: (super dangerous)
3) “Congressional Dems have grown so frustrated with WH testing efforts that as part of any aid agreement, they insisted on language to carry out a far more prescriptive national program for administering and distributing tests. WH negotiators resisted those demands for months”
BREAKING—Trump WH had installed 2 political operatives at CDC to control #COVID19 information, sometimes at odds with scientific evidence. The 2 appointees, w/ no public health background, tasked w/ “keeping eye” on Dr Redfield & scientists. Dystopian. 🧵 apnews.com/article/electi…
2) Reminds me of the old song about Soviet commissars—or political officers who watched over all activities to assure political purity.
If anyone remember “The Hunt for Red October”, they were the infiltrators to quash disloyal activities.
3) “The appointments were part of a push to get more “politicals” into the CDC to help control messaging after a handful of leaks were “upsetting the apple cart,” said an administration official.
📍TRUMP WH MUZZLED CDC—Trump wanted churches open. So, WH told the CDC to remove church “choir singing” from guidelines of risky #COVID19 activities. CDC refused to edit & published anyway. WH Pence office went ballistic—forced deletion from CDC website. 🧵propublica.org/article/inside…
2) “Senior CDC staff describe waging battles that are as much about protecting science from the White House as protecting the public from COVID-19. It is a war that they have, more often than not, lost.
3) “Employees spoke openly about their “hill to die on” — the political interference that would prompt them to leave. Yet again and again, they surrendered and did as they were told. It wasn’t just worries over paying mortgages or forfeiting the prestige of the job.
📍NEW: CDC reports an outbreak at an indoor recreational ice hockey near Tampa Bay, Florida. 15 players & staff fell in soon after, 13 confirmed #COVID19 positive. Both teams infected—and not even everyone tested. Only 1 spectator (not tested). Worrying outbreak for any sport. 🧵
2) “Teams A and B, each consisting of 11 players (typically six on the ice and five on the bench at any given time), included men aged 19–53 years. During the 5 days after the game, 15 persons (14 of the 22 players and a rink staff) experienced symptoms: 13 of 15 lab confirmed.
3) “On June 19, 2020, the Florida Department of Health was notified of a team A player (the index patient) who experienced fever, cough, sore throat, and a headache beginning on June 17, the day after he had participated in an evening game; 2 days later, test positive.
📍Trump’s “immunity” is likely artificial & temporary says experts. His synthetic antibodies could actually prevent his body from making own. Regeneron antibodies have a half life of 21–25 days—thus, by Oct 23, half gone by then. #COVID19#TrumpCovid 🧵 nytimes.com/2020/10/14/hea…
2) “Without replenishment, this decline may leave Mr. Trump even more susceptible to the virus than most patients who have recovered from Covid-19, several experts warned.”
3) “Moreover, the steroid treatment the president received early in the course of his illness suppresses the body’s natural immune response, including its propensity to make antibodies of its own.”