Discover and read the best of Twitter Threads about #Hydroxychloroquine

Most recents (24)

Based on published #HCQ studies & case-controlled clinical trials, HCQ has significant efficacy in early treatment of #COVID19: PRE-exposure prophylaxis & early POST-exposure treatment. Recent NEJM RCT focused on NEITHER of these 2 key groups but rather: POST-exposure prophylaxis
2/ Here’s link to NEJM #HCQ RCT published today on POST-exposure prophylaxis given up to 4d AFTER exposure. Disturbing that science was again politically sensationalized by media before study was even published w/quotes from MD with #Gilead #BigPharma COI…
3/ “The results reported by Boulware et al. are more provocative than definitive, suggesting the potential prevention benefit(s) of #Hydroxychloroquine remain to be determined,” concluded Dr. Myron Cohen MD in NEJM editorial re recent NEJM HCQ #COVID19 RCT…
Read 4 tweets
Randomized controlled trial in 821 healthy people exposed to #COVID19 patients.
* @NEJM paper today
* Participants were randomly assigned to receive either #hydroxychloroquine or a placebo
* No significant difference between rates at which people in either group got ill
Link to the paper given by @nytimes does not work (yet?) and article does not appear on @NEJM website as of now. Scheduled to come out today, though.
Here is NYTimes link that does not yet work:…
Apparently it will go online in 30 min, at 5 pm ET today, hopefully with this link:…
HT: @fxcoudert @Germhunter @hokkos @houndcl et al.

Read 3 tweets
🚨BREAKING: @realDonaldTrump's favorite drug–#hydroxychloroquine–did NOT prevent infection in people exposed to #coronavirus.

This randomized, double-blinded, placebo-controlled trial enrolled >800 adults who'd been exposed to someone with #COVID19.…
The study randomized 800 participants to get either #hydroxychloroquine or placebo ("placebo-controlled") and was double-blinded (neither participants nor researchers knew what the participants received). This is the gold standard for clinical trials.…
To date, no rigorous study has shown that #hydroxychloroquine is effective in treating or preventing #COVID19, and some studies have shown increased risk of potentially FATAL arrhythmias and DEATH.

There's ZERO reason for this drug to be given to patients infected with #COVID19.
Read 3 tweets
Both @NEJM & @TheLancet are reviewing #Hydroxychloroquine papers they pub'ed, authored by a company called Surgisphere, claiming death rates increased among #COVID19 patients taking the drug. The company seems highly suspect, cherry-picking results.…
2/ Because of these papers @WHO stopped supporting clinical trials of #Hydroxychloroquine for #COVID19 treatment.
Now that use of the drug is thoroughly politicized by, on one side, #Trump & on the other, by Surgisphere it may be impossible to get a valid scientific consensus.
After reading the @ScienceMagazine paper I'm getting quesey about all of the "warp speed" #COVID19 treatment and #vaccine work. Every journal is rushing peer review, regulatory agencys are under pressure to speed approvals, & there's too much lose $$.…
Read 3 tweets
The #FakeNewsMedia likes to use the words “peaceful” and “protests” in the same sentence to describe this 👇 ImageImageImageImage
If these #AntifaTerrorists are truly fighting for change with the #BlackLivesMattter movement against “#SystemicRacism”, then why wouldn’t they start by burning down all the #PlannedParenthood centers that are committing #Genocide within the Black Communities?
Read 17 tweets
A new thread on another #hydroxychloroquine study in a major medical journal from the same study group as posted in @TheLancet and for which the data has been shown to be impossible.

This time the @NEJM

Hold on to your hats
You need to have a bit of statistics background to understand this. It's all about the variance. When you have different groups they vary. The more numbers you have in each group, the less the variance (proportionally).

Different groups would never have the same variance
Except in this study!

Not only do all these age groups have the same variance in this chart, but what *should* happen is that very small groups would have big variance (confidence intervals on this chart).

Well, it appears there are a lot of hypertensive teens with #covid19 Image
Read 26 tweets
What does "science-based" mean to you?

Ethical conduct of research requires "equipoise", which means there is genuine uncertainty between the options studied. There is simply no good data on #hydroxychloroquine and its use as prevention or treatment of mild #COVID19.
The exisiting observational studies of hospitalized patients not only tell us nothing about prevention/mild disease, but now are plagued w/ allegations of data fabrication #LancetGate. A well-designed, randomized controlled trial IS the most "science-based" option right now.
Myself & my co-investigators @TulaneMedicine @TulaneSPHTM @UW have been trying to answer these unknowns about hydroxychloroquine #HCQ in a scientifically sound, safe, ethical way, but have been receiving online abuse for our efforts, and this needs to STOP.
Read 4 tweets
The more I read the #Lancetgate #hydroxychloroquine study the more implausible any of it seems ~40% of ALL African #COVID19 deaths captured in a comprehensive electronic hospital database and cared for in beds with cardiac monitoring. No ethical approvals needed. Really? 1/15
I know there has been extensive comment on the paper, but as someone who has worked with a lot of routine hospital data in African settings I wanted to make a few specific comments. Link to the paper here…
Here is Table S3; 4402 hospitalised patients from Africa and 437 deaths. They say they censored cases on 14th April and deaths on 21st, at which points there had been a TOTAL of 15291 #COVID19 cases (in- and out-patients) and 1155 deaths on the entire continent 3/15
Read 16 tweets
It has been a hard week for me watching what I consider to be one of the biggest health scandals of our time occur in relation to two affordable, widely available drugs that may offer potential benefit to patients with #COVID-19 (#hydroxychloroquine + ivermectin)
2/ Let me explain. First, I have been nauseous to see certain scientists in positions of great authority categorically dismiss the use of #hydroxychloroquine in any stage of #COVID-19 based, not off the literature, but off personal grudges either against Trump or MDs like Raoult
3/ These are scientists that have 100,000+ followers + speak to the media that shapes the globe’s #COVID-19 decisions…that, as far as I can tell, have not tried to understand the mechanisms of action by which hydroxychloroquine might benefit COVID-19. See
Read 14 tweets
Merci à tous pour votre soutien !
La vidéo injustement censurée par YouTube et de retour... Sans AUCUNE explication, aucun message, RIEN.

Cette opacité ne peut que détruire le lien de confiance, quand il existe, entre les créateurs et la plateforme.

Tant qu'on y est, jetez donc un œil à nos autres vidéos sur le même thème : #Covid19 #raoult #Hydroxychloroquine,
Et aussi cette vidéo là, qui ne citait alors aucun nom mais rappelait l'existence d'individus toxiques et malheureusement très puissants dans le monde de la science.

Read 4 tweets
Are you awake yet?

Who will you listen to?
⛔️ Are there instruments of propaganda active in the world?
💠 If so, what are they?
🈶 Why should you care?

Ignorance is a choice. #FreedomIsntFree

The Gist 1

➡️ 2.1 Million in Nursing Homes (0.62% of US pop.)
➡️ 42% of #Covid19 deaths in US occured in Nursing Homes

% of all US COVID deaths happening in Nursing Homes:
Ohio 70%
Minnesota 81%
Pennsylvania 69%
The Gist 2:

New York, New Jersey, Michigan (Democrat) governors made regulation REQUIRING nursing homes accept patients with Active COVID infections.

Yes, you read that correctly.

Why? Coincidence? Reasons? Justification? Ignorance?…
Read 11 tweets
I see no reason to stop ongoing RCTs for #hydroxychloroquine. The @MRMehraMD/@TheLancet comparison suffers from enough statistical bias to mask a beneficial effect of the drug. We need RCT data to know whether #hydroxychloroquine is effective for #COVID19 or not. #EBM THREAD 1/18
Short version: The study isn't an RCT. Is subject to confounding bias. Adjustments (controls/matching) are far from adequate to address bias. Tipping-pt analysis shows bias is strong enough to flip a true beneficial impact of #hydroxychloroquine to negative. #MedicalTwitter 2/18
Let's unpack this: The challenge with non-experimental studies is that you're comparing treatment and control groups that don't resemble each other because doctors determined who got the treatment instead of using a "coin flip" like in an RCT. 3/18
Read 19 tweets
#QAlert 5/27/20 This will be my THREAD for all #QPosts for Wednesday , May 27, 2020. YOUR VOICE AND YOUR VOTE ARE WHAT MATTERS MOST. and more!

Happy Birthday to my Mom. Thank you for you. I love you. 🙏🏼

Let’s Go!
#QAnon #WWG1WGA………
If elderly most at risk [known][knowingly] why order COVID-19 positive patients back into nursing homes?
Hospital capacity?
USNS Comfort capacity?
Ignorant [A] or deliberate [B]?
[Accountability] options 👇🏼
Read 14 tweets
1/11 THE LANCET #HYDROXYCHLOROQUINE STUDY: CONFLICT OF INTERESTS? This observational cohort study was signed by 4 cardiologists , not a virologist, epidemiologist or statistician signed the study. But let´s see who they are: 1. MD Mandeep Mehra: Chief Cardiologist in the...
2/11 ....Brigham and Women´s hospital in Boston. This hospital has been running since march two clinical trials on Remdesevir, under contract by Gilead, an antiviral drug that could be directly affected by unpatented and low cost Hydroxychloroquine.…
3/11 MD Mehra also participated in a symposium COVID19 hosted by SEIMC (Barcelona) and sponsored by Gilead. He was one of the conference speakers.…
Read 11 tweets
🇮🇹 Dr Andrea Savarino - Istituto Superiore di Sanità

Ce Docteur remet en cause l'étude du Lancet

L'étude du #Lancet "est affectée par une distribution non homogène des facteurs de risques préexistants"


"les groupes traités par #chloroquine / #hydroxychloroquine contenaient, par rapport aux témoins, une prévalence plus élevée de fumeurs, d'hypertenseurs et avaient en moyenne un indice de masse corporelle (IMC) plus élevé"

"Selon les mêmes analyses des mêmes auteurs, certains de ces facteurs tels que l'hypertension se sont révélés être des prédicteurs de mortalité dans l'ensemble de la cohorte de patients considérés, indépendamment de l'utilisation ou non de CQ / HCQ"

Read 6 tweets
🔴BRESIL Lettre de scientifiques

Une lettre ouverte à lire absolument !
Le monde scientifique se rebelle ! Bravo

Rapide résumé d'extraits traduits ici (je ne peux pas tout traduire )


Des groupes d"experts" ou de scientifiques célèbres de YouTube, dont bcq sont encore des débutants en science, ayant une expérience minimale ou inexistante dans la lutte contre les pandémies, sont sélectionnés par l'establishment et les médias
...pour donner une «aura scientifique» à la l'isolement cellulaire et la condamnation de l'hydroxychloroquine (HCQ) comme médicament inefficace; pire, comme un poison mortel....

Read 13 tweets
The Story so far...#DominicCummings (#DomCum) Tour 2020

19.03.20: The Prime Minister, #BorisJohnson makes a nationwide statement about #CoronaVirus aka #Covid19……

23.03.20: The Prime Minister, #BorisJohnson announces measures for a nationwide #UK #Lockdown as a response to contain #CoronaVirus aka #Covid19…
23.03.20: The Prime Minister addresses the nation once more.

"That is why we have given the clear instruction that people must stay at home – unless they have one of the reasons we have set out, & with your help we will slow the spread of the disease."…
Read 29 tweets
1. #QAnon Welcome to the Shadow Presidency of Barack H. Obama. Adm Rogers didn't retire till June 1 2018. He'd met President elect Trump in TT November 17th, 2016 in SCIF w/o informing Clapper. Trump moved out next day, & WaPo reported same day 11/18/16 Adm R ought be removed. #Q
2. #QAnon… Rogers knew [Hussein]'d ordered prevention of sharing of intel on #RussiaHoax spy-op on Trump team, w layers of protection, Mueller, AS WB's, impeachment, now accidentally on purpose spill of #WuhanVirus. #Q
Read 55 tweets
Etude du #Lancet, dans les intérêts/financements reçus des auteurs, le 1er labo cité: Abbott, ancien nom de ABBVIE, qui fabrique le Ritonavir et le Lopinavir! Un labo qui a intérêt à décrédibiliser l'#hydroxychloroquine contre le #coronavirus! #COVIDー…
Allons voir les autres ... On ajoute le labo Mesoblast qui eux font la promotion de leur médoc à base de cellules souches contre le #Covid_19. Vous en voulez encore? #coronavirus #thelancet…
Il y a aussi le labo Janssen qui collabore avec le labo #Gilead en Irlande, et qui a nommé Jonathan Pentel comme directeur Nouveaux Produits, qui a travaillé pour #Gilead depuis 2011 jusque 2017.…
Read 11 tweets
Natural immunity looking better all the time. Korean tests of naturally recovered COVID-19 patients showed they are NON-INFECTIVE. This vaccine (an RNA vaccine, BTW) doesn't work as well.

This failure is why Gates/CEPI is moving his money to a different, more classic vaccine.
Now one sees why being a "benefactor" has so much "information privilege" - insider info which GROWS THE MONEY. When a guy like Gates doesn't take losses, and isn't touchable on "insider information" because it's all charity work "under an emergency" - well, do the math.
I'm not sure the "cure" of government anti-corruption shakedown on insider info (e.g., trading) isn't worse than the "disease" of insider info itself, so my attitude is "whatever".

But WE THE PEOPLE need to retain the right to criticize MONEY-INFLUENCED SCIENCE at all times.
Read 14 tweets
The Lancet article attached made the claim that #Hydroxychloroquine doesn't work & that it kills people. Their goal was to prove Pres Trump wrong.

I just analyzed the data and am going to destroy this fraudulent junk science hit-job on #HCQ.

Let's start with conflicting research by Dr. Daniel J. Wallace at Cedars-Sinai Hospital in California who has the largest medical practice in the US treating Lupus patients. He has used #HCQ safely w/ his patients for >30 yrs. 0 of them have #Covid19…
The Lancet did not do a clinical trial. They scoured the world looking for data to support their bias against #HCQ.

HCQ is proven already to be less toxic than Chloroquine.

So Lancet added people given Chloroquine to their HCQ group. Lumped together. Why? To bias the data.
Read 9 tweets
Please read all the way through!

1. I had a video appointment with my Dr. today. I asked him about #COVID19 cases - he said there are almost none. I also asked if they are prescribing the #Hydroxychloroquine protocol. He said only for those hospitalized.
2. He said the few positive cases they are seeing are mostly #asymptomatic and do not need anything except to be periodically monitored to make sure they are OK. We joked about how #COVID has cured all other diseases because nobody dies of anything but COVID now.
3. He told me something very disturbing that I bet most people do not know. He said almost every death is being labeled as #COVID because the hospital makes more money - but here is the disturbing part: most life insurance policies have a “#pandemicexclusion”.
Read 3 tweets
A Shabbat Vision Thread

1) #Hydroxychloroquine is the new #RedPill.

We are living in a battle of narratives. My patients ask me to comment from my medical perspective about what our future looks like in this battle with #COVID19. I tell them I see two possible futures.
2) One future looks like what we have now. We are frightened, keeping physically distant, wearing masks, avoiding crowds, not going to movies or restaurants. The economy has soured. Unemployment is rampant. The only people working are those deemed essential or those...
3)...who can work remotely from the safety of their home. In this future, leaders say salvation will come in the form of a vaccine, but until the vaccine arrives, much has been lost. Businesses go bankrupt. There is uncertainty as to how much immunity the vaccine will...
Read 18 tweets
Here's why I think this #hrdoxychloroquine "study" data is fake…

A thread....
@99freemind @realDonaldTrump @PressSec
(1) the study says that they received data from 600 hospitals up to mid-April, and it was published end-May.

This is impossible. If you have ever collected clinical research data you will know how impossible it is.
You have to get doctors to enter information and they are completely unreliable, requiring to be chased all the time. If you're lucky some units have a research nurse who is much better, but the data reports are either on paper (needing mailing/faxing) or an electronic repository
Read 35 tweets

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