About to start the session about the study that shows that High-dose rifapentine with moxifloxacin can shorten treatment time by a third for people with pulmonary #TB #UnionConf 
📣 The #s31tb session starts!
#s31tb is the largest drug-sensitive #tb treatment trial in decades. It tested two arms vs. control aiming to shorten treatment to 4 months:
👉🏽substituting rifampicin with high-dose of rifapentine, &
👉🏽same + ethambutol for moxifloxacin
#s31tb is the largest drug-sensitive #tb treatment trial in decades. It tested two arms vs. control aiming to shorten treatment to 4 months:
👉🏽substituting rifampicin with high-dose of rifapentine, &
👉🏽same + ethambutol for moxifloxacin
🧫Innovation: the #S31TB enrolled 2,500 participants in 13 countries and included adolescents over 12, people living with HIV and people with cavitary #TB.
🤝Collaboration! #S31TB was an effort by two US-funded research networks: TBTC (at @CDC_TB) and @ACTGNetwork (at @NIH)
🤝Collaboration! #S31TB was an effort by two US-funded research networks: TBTC (at @CDC_TB) and @ACTGNetwork (at @NIH)
📣 #S31TB The arm testing high dose rifapentine and moxifloxacin shows noninferiority.
Aka: Finally: a safe, effective and shorter #tuberculosis treatment! People will be cured in four months instead of six!
This major scientific advance is thanks to public 💵, a public good!
Aka: Finally: a safe, effective and shorter #tuberculosis treatment! People will be cured in four months instead of six!
This major scientific advance is thanks to public 💵, a public good!
Yes!
We finally have a safe, effective and shorter #tuberculosis treatment! People will be cured in four months instead of six!
We finally have a safe, effective and shorter #tuberculosis treatment! People will be cured in four months instead of six!
📣 The new 4-month regimen is safe and effective in all studied groups.
We need to move forward and make the new treatment accessible as soon as possible – first in the 13 countries involved in #S31TB 🌍
We need to move forward and make the new treatment accessible as soon as possible – first in the 13 countries involved in #S31TB 🌍
Community engagement 💪🏽 was paramount in #S31TB design and implementation. High retention and adherence in all arms
👩🏽🔬Researchers adapted the design of this study to meet the needs and requests of #TB-affected communities in addition to relevant response to scientific questions
👩🏽🔬Researchers adapted the design of this study to meet the needs and requests of #TB-affected communities in addition to relevant response to scientific questions
📣 The #tuberculosis 4-month regimen benefits patients, health providers and health systems.
👏🏽@WHO Guidelines will need to adapt to this new era of treatment for sensitive pulmonary 🫁 TB.
👏🏽@WHO Guidelines will need to adapt to this new era of treatment for sensitive pulmonary 🫁 TB.
➡️ Dr. Grace Muzanye, Senior Clinical Coordinator (Kampala), summarizes perfectly the importance of this new 4-month regimen with this slide.
💊40 years since we got the six months treatment for #TB!
#UnionConf #EndTB
💊40 years since we got the six months treatment for #TB!
#UnionConf #EndTB
Do you have questions or doubts about this trial and the amazing results?
Do you want to ask how they affect our communities?
Come to tomorrow’s session at #communityconnect #UnionConf:
📅 22/oct
⌚️ 2pm US Eastern/ 8pm CET
Tuit.cat/5ivrh
Do you want to ask how they affect our communities?
Come to tomorrow’s session at #communityconnect #UnionConf:
📅 22/oct
⌚️ 2pm US Eastern/ 8pm CET
Tuit.cat/5ivrh
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