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Ross Levine Profile picture
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28 Oct, 6 tweets, 2 min read
Mark, so wonderful to see your work, leadership, and mentorship recognized.
1. You are the consummate scientist, and you and your group's contributions to cancer epigenetics, leukemia biology, epigenetic therapies, and immune-oncology are original, impactful, and greatly influence how we think about cancer biology and do our own work.
2. You're an amazing mentor, institutional/international leader, and colleague.
3. I also consider you a dear friend who is an amazing dad/husband and role model. Sarah-Jane and you are people we admire, appreciate, and emulate.
4. Please take a moment to celebrate and to realize how important you are to us and the field, and appreciate this most wonderful recognition.
5. And we need to toast with a zoom beer soon with @JohnstoneRicky and @Armstrong_dfci!

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More from @rosslevinemd

Ross Levine Profile picture
28 Oct
OK tweeps, today is the day, our work on single cell analysis of clonal evolution and myeloid transformation is out, led by the best in the biz, @lindemilesphd and @bowman_rl
nature.com/articles/s4158…
1. First things first; thanks to everyone who helped us with this awesome story; @TheDoctorIsVin, Chris F. and Minal P. in @chm, @levinelab (Tiff!), @duruthy & @MissionBio, @SaraMeyerLab, @RaajitRampal , @Kellybolton, @ahmetz, Michael Bowman, Adam Abate and team->thank you!
2. Please also see awesome paper by @DrKTakahashi and co at @NatureComms and preprint by Adam Abate on DNA/protein sc sequencing/tech dev. All together the collective work is so cool!
Read 22 tweets
Ross Levine Profile picture
26 Oct
Part 2 of an awesome week of great collaborative studies coming out; the Beat AML Master Trial! An amazing effort led by Amy Burd @LLSResearch , John Byrd @OSUCCC_James , Brian Druker @OHSUNews and myself @SloanKettering.

nature.com/articles/s4159…
1.This study started in a small hotel conference room at ASH 2015; a group of us got together and wondered if it was time for a genomic-guided clinical trial in AML. The LLS and their CEO @LouisJDeGennaro saw the possibility, and challenged us to make it happen
2.After a year of discussions including Sunday AM calls, many conversations with our amazing colleagues at the FDA, and lots of discussions with academic and industry partners->we decided to move forward and make it happen
Read 13 tweets
Ross Levine Profile picture
11 Mar
PIs. ask yourself and your lab some important questions today.
1. If someone can do their job at home (or part of their job), are you letting them do it?
2. Did you freeze down aliquots of your ongoing cell culture experiments in case you have to stop ongoing experiments?
3. Is your animal colony tightly maintained, and can a "skeleton" crew of people from the lab take turns maintaining it if needed?
4. If anyone in your group has child-care responsibilities due to school closures etc->is it clear they should go home immediately?
Read 7 tweets
Ross Levine Profile picture
22 Jan
One of the hardest things to figure out as a PI, especially a young PI, is "when to hold em and when to fold em" with respect to appealing/revising a paper with tough reviews. A few thoughts
1. Don't ever figure this out alone, or even just within your lab. Ask peers, mentors and THE EDITOR if the revision is feasible
2. If there are experiments suggested by reviewers which you feel are not reasonable or out of scope, discuss with the editor before you begin revising (and not 6 months later!)
Read 9 tweets
Ross Levine Profile picture
20 Jan
The chalk talk; my own personal two cents...
1. The goal of a chalk talk is not to show how much you know, or to show all the ideas and projects you can think or or actually accomplish
2) It is to show
A. feasible research plan which will lead to results, papers and grants
B. ability to take in others' ideas/questions, to respond thoughtfully and engage the people in the room in a back and forth
C. get everyone in the room excited to have you as a colleague
3. The majority of the chalk talk should be on your major planned area of study->down the fairway. Someone should be able to see how it will transmit into a grant (R01) and into papers. Lay it out as close to a grant as you can and make it easy for the audience to see...
Read 17 tweets
Ross Levine Profile picture
16 Jan
It is now interview season! a few thoughts for those going on job interviews for lab based PI positions.
1) Get there the night before the interview, even if no dinner. If no dinner scheduled and you have a friend there, go out for a bite and get the real scoop
2) Look at one paper from each person you will meet, and get the overall gist. If the conversation in any one-on-one stalls, ask them about this paper and their work! we all love to talk about our own science and you can soak it in...
3) stick to your routine. if you normally go to the gym/exercise before your work day at home, do the same. I found that I was always up early before interview days and had to do something to reduce my jitters.
Read 11 tweets

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