Reduced salivary production leads to more than just the symptom of dry mouth!
💠Decreased lubrication ➡️ difficulty speaking and swallowing
💠Loss of remineralizing saliva ➡️ cavities and tooth decay
💠Increased infections, including candidiasis and periodontal disease
Prevent cavities and tooth decay:
🦷Prescription fluoride varnish every 3 months
🦷High fluoride toothpastes (1.1%) once a day
🦷Remineralizing rinses like Caphosol or NeutraSal
🦷Chlorhexidine if any periodontal/gingival disease
Other ways to lubricate the mouth:
💠Vitamin E (break the capsules open to get to the oil)
💠Mineral oil
💠Numerous OTC rinses, gels, and lozenges
Now for the eyes! Again, dry eyes in Sjogren's go way beyond an annoying symptom:
-Dry eyes actually decrease visual acuity and can interfere with activities like reading
-Chronic conjunctivitis
-Keratitis, which can lead to corneal melt/perforation and/or scarring
Decreased Schirmer testing tends to be a later finding (and cutoff of 5 mm is a little arbitrary), so send your patients to the ophthalmologist early for tear breakup time testing and/or ocular surface staining
🚨Lacrimal gland enlargement is a RARE finding in #Sjogrens.🚨 Dr. Akpak says in 20 years of being a Sjogren's ophthalmologist, she has NEVER seen it. Instead think:
👉Sarcoidosis
👉Lymphoma
👉IgG4RD
👉Thyroid eye disease
How to treat dry eye in Sjogren's:
👀Eliminate offending systemic/topical meds
👀Ocular lubricants (artificial tears should be preservative free!)
👀Lid hygiene, warm compresses
👀Overnight treatments like ointments/gels or moisture chamber devices
👀Pilocarpine or cevimeline
Treatments Ophtho can offer:
👁️Punctal occlusion
👁️Topical treatments like cyclosporine eyedrops
👁️Treat other contributing conditions, like ocular rosacea
👁️Autologous serum eye drops
👁️Scleral lenses
And more!
These talks were great reminders of how multidisciplinary care can be a huge asset to Sjogren's patients. Give your patients the advantage of having not just a smart rheumatologist, but a smart dentist and ophthalmologist as well!
HRCT is incredibly important!
-Different ILD patterns predict outcomes and response to therapy
-Look for non-ILD findings that impact diagnosis and treatment: esophageal dilation, pulmonary artery dilation, pleuritis, tumors
As a rheumatologist, NEVER forget that ILD can come first in myositis. With ILD + myositis specific antibody, you should have an extremely high suspicion for myositis even if there isn't extrapulmonary disease (yet). #rheumtwitter#ildtwitter
#ACR20 Evaluation and Treatment of Systemic Sclerosis-ILD in the New Decade with Dr. Anna Hoffmann-Vold
(a live-tweet)
Some background facts all rheumatologists need to know:
👉ILD often arises early in the course of SSc
👉Not just in dcSSc, or just with Scl70 Ab
👉MAJOR cause of morbidity and mortality, even when degree of fibrosis is not severe
Screen for this with HRCT. PFTs alone will miss most cases of SSc-ILD!
T-5 days until rheum boards! 🙃 Today, let’s review MSK manifestations of endocrine disease. We’ve got it all: diabetes, hypothyroid, hyperthyroid, parathyroid...ready? #rheumtwitter #medtwitter #tweetorial #FOAMed
Let’s start with diabetes. People with diabetes tend to produce more “advanced glycation end products,” which are metabolic byproducts that get deposited into tissues and make tissues thicker, stiffer, and weaker.
The worse the glycemic control, the more AGEs get deposited, and the worse the stiffness gets. This phenom is at the root of a LOT of diabetes MSK issues.