2) It’s closer to 3.6 million. The estimate does not include an approximately equal number of latent infections among people who caught the virus in recent days and can’t pass it on yet because it is still incubating (waiting to become contagious).
3) This is much bigger than the officially diagnosed number of cases— which is an average of 477/mil/day in US.
If we assume each case is infectious for ~10 days, the 3.6 million is roughly 2.3x the average number of new cases recorded in the past week *10 days.
4) above is not exact, because severe hospitalized cases can be infectious for up to 20 days. But average infectious period is 10 days. As a minimum, it implies we are missing ~56% of all infectious cases (1-(1/(2.28))). Better than 10-20x before. But still many cases undetected.
5) And above is just for infectious cases. If we assume incubation is on average 5 days, there are still up 5 days more worth of undetected cases waiting to be soon infectious. Tons more cases undetected than our daily officially confirmed case numbers. This is not good.
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BREAKING—wow—WHO just recommended **against** the use of @GileadSciences’s drug remdesivir in hospitalized #COVID19 patients, citing “there is currently no evidence that remdesivir improves survival or reduces need for ventilation in these patients”. 🧵
👉 who.int/news-room/feat…
2) “data from over 7000 patients across the 4 trials were considered.
The evidence suggested no important effect on mortality, need for mechanical ventilation, time to clinical improvement, and other patient-important outcomes.
The guideline development group...”
3) “recognized that more research is needed, especially to provide higher certainty of evidence for specific groups of patients. They supported continued enrollment in trials evaluating remdesivir.”
FOCUS ON AIRBORNE, *not* surfaces. Scientists increasingly say that there is little to no evidence that contaminated surfaces can spread the virus. Health officials are being urged to focus instead on improving ventilation and filtration of indoor air. nytimes.com/2020/11/18/wor…
2) “A lot of time, energy and money is being wasted on surface disinfection and, more importantly, diverting attention and resources away from preventing airborne transmission”
3) “People are removing masks for lunch or when they get back to their cubicle because they assume their cubicle is their private space... But remember: The air you’re breathing in is basically communal.”
NEW RIGHT WING ATTACK—Hydroxychloroquine misinformation & conspiracy theories are back. This time, peddled by US gop senators and trolls attacking Professor @ashishkjha (and Dean of Brown SPH). It’s really surreal and crazy this happening in pandemic. #COVID19
RATIONING CARE—El Paso has been so depleted by #COVID19 that besides moving bodies with inmates, hospitals are nearing a point where health workers could decide who gets care and who doesn’t. EP begging TX gov for national guard, but Abbott blocks so far. texastribune.org/2020/11/18/el-…
2) There are now 218 deceased bodies stuff in those refrigerated morgue trailers according to El Paso county judge.
Listen up—if there is a scientist who is a *hero* besides Fauci, it’s Dr Kim Prather @kprather88–world renowned aerosol expert. Not many know, but it was Kim who alerted Fauci on airborne #SARSCoV2. If it weren’t for her, we still wouldn’t have airborne guidelines. She’s my hero.
2) Dr Prather is also an extremely rare “double inductee” in both the National Academy of Science & National Academy of Engineering (harder than winning Triple Crown). She wrote “Tony” (Fauci) a strong note of concern, and made Fauci see his blind spot on airborne aerosols. See👇
3) Basically, Dr Fauci admits above (and elsewhere) it was a group led by @kprather88 (& @CorsIAQ) that approached him & explained small aerosols Microdroplets are airborne. Here is Kim explaining the difference between droplets & aerosols with @DrLaPook.
2) and if hosting a gathering, they recommend virtual or “Have a small outdoor meal with family and friends who live in your community.”
3) the reason we haven’t even seen the worst yet is because of death lag. All the surging cases so far this month won’t translate into deaths for 3 weeks — until after Thanksgiving / into December.