👇IMPORTANT EXPLANATION to vaccine questions. @michaelmina_lab explains it all:

📌“why is a vaccine is a more trusted source of immunity, if already have antibodies & T-Cell response?”

📌“How does vaccine give me more protection than some earlier immunity?” (@dianaberrent asks)
2) In addition to Dr Mina’s above explanation, @VirusesImmunity also explains her rational:
3) Further, noted earlier that the Pfizer & Moderna vaccines both showed better antibody binding & neutralization in vaccinated people in their P1 trials, than convalescent natural infected survivors.

Hence, another reason vaccine better than Scott Atlas’s “herd”. #COVID19
4) As @michaelmina_lab explains, vaccine is more targeted to the #SARSCoV2 receptor while natural infection has a more “choose your own adventure” what parts of virus one develops antibodies to. Targeted likely better.
5) The analogy @michaelmina_lab explains is that natural infection can develop non-useful antibody recognition like to a less useful “pinky toe” part.

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More from @DrEricDing

23 Nov
UTTERLY SOBERING—cases rising so fast that we will likely see 3000 deaths a day by end of year. That is one 9/11 ✈️✈️✈️✈️ death toll *per day*!

➡️ Christmas 2020 🎄might be cancelled if this keeps up.

(Analysis by my FAS Team). #COVID19 Image
2) We can add more beds but we can’t just add more doctors and nurses. Especially if they keep falling ill or dying.

N Dakota is now asking infected doctors to keep working.

Thousands of doctors and nurses not so lucky.
3) Horrendous thing is that many places like the Dakotas have even given up on contact tracing.
Read 5 tweets
23 Nov
“I guarantee you...”

Worst words ever spoken. And Cruz has spoken a lot of bad takes. #COVID19
I hope these famous words will be forever etched on Cruz’s tombstone someday. #COVID19 ImageImageImageImage
Let’s remember all the HCWs who have died and continue to fall ill from #COVID19. It’s not an election hoax to them.
Read 4 tweets
23 Nov
DEVASTATING—A contact tracer says North Dakota almost given up tracing: “unless pregnant, we don’t gather any history. Unless their job is health care, or work/attend K-12 schools, we don’t notify their employers”. 🤦🏻‍♂️

👇 Horrendous story #COVID19. washingtonpost.com/outlook/2020/1… Image
2) “This is what an emergency looks like in North Dakota: Every day seems to break a record for new infections. Even if hospitals have beds, they don’t have enough staff; the governor recently proposed allowing HC workers who test positive to continue working in #COVID19 units.”
3) please think of all the healthcare workers risking their lives too. So many have died. Beg you, please.
Read 4 tweets
23 Nov
BREAKING—Oxford/Astrazeneca vaccine is 70% effective overall. But one of its dosing regimens of low-then-high yields 90% effectiveness.

Oxford #COVID19 vaccine cheaper than the Pfizer & Moderna vaccines, and does *not* does not require freezing transport.
2) When volunteers were given two "high" doses the protection was 62%, but this rose to 90% when people were given a "low" dose followed by a high one. Not clear why yet.

The 90% effectiveness data was "intriguing" and would mean "we would have a lot more doses to distribute."
3) There were also lower levels of asymptomatic infection in the low followed by high dose group which "means we might be able to halt the virus in its tracks," Prof Pollard said.

In the UK there are 4 million doses ready to go, with another 96 million to be delivered.
Read 9 tweets
22 Nov
CRITICAL—a negative coronavirus test is **NOT** a ticket to freely socialize without precautions—many are dangerously misguided that it is. It does not negate quarantining, masking & distancing. Here is why 🧵. #COVID19 news.yahoo.com/no-negative-co…
2) There is a virus buildup time — called incubation time—until one usually shows symptoms & viral load high enough to the reliably detected. Usually incubation is 5-6 days, but can be 1-14 days or longer. But if you test too early before viral load builds up, you’ll test neg. Image
3) This does not mean testing is bad—if anything we need more frequent testing. But you can test negative 4 days straight and then positive on day 5. That’s what happened to WH staff K-McEnany and S-Miller—4 negatives before 5th positive. Most people don’t have that luxury. Image
Read 11 tweets
22 Nov
Millions Americans can't celebrate Thanksgiving with their family because the coronavirus gave their relatives "cold dead hands".

Taunting people to "Come and take it" is so irresponsible during pandemic. #COVID19
2) Meanwhile, Cruz can help out at the local morgue if he has time to taunt instead of trying to pass a Coronavirus Relief Bill.
3) Or Cruz can help out at the local El Paso ICU with this nurse in “the pit”
Read 5 tweets

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