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7 Dec, 4 tweets, 1 min read
Despite this story going massively viral (because it is about penises) I reckon it's worth pointing out that the evidence or this statement seems to be mostly theoretical
The only scientific paper referenced that I can find anywhere is this piece from July that basically says that there are plausible pathways for COVID-19 to cause ED so we should watch out for it

pubmed.ncbi.nlm.nih.gov/32661947/
I mean, sure, the pathways seem plausible, but imo the time to be really worried about something is when we've got evidence that it is a problem
Anyway, I suspect that the fact that there isn't even a case series on ED post COVID-19 when there are papers on literally everything else suggests that while this may be a concern it is probably not quite as scary as the headline suggests

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More from @GidMK

Health Nerd Profile picture
9 Dec
Lockdowns have mostly not been associated with a large increase in suicide rates: a thread of evidence (CW: suicide, mental health) 🧵
Since this has been a major talking point throughout the pandemic, I thought I'd collate the now quite large evidence-base showing that suicide rates have mostly remained steady during lockdowns/COVID times
1. Queensland, Australia

Slight decrease in suicide rates after emergency announced, no statistical change over lockdown vs previous years thelancet.com/journals/lanps… Image
Read 12 tweets
Health Nerd Profile picture
8 Dec
Big news! Our systematic review and meta-analysis of the age stratified IFR of COVID-19 with @BillHanage, Andy Levin, and others has now been published in the European Journal of Epidemiology

link.springer.com/article/10.100…
The key figure from the paper - your risk of death from COVID-19 goes up exponentially by age:

1 in 50,000 at age 20
1 in 1,500 at age 40
1 in 130 at age 60
1 in 12 at age 80 Image
The other big thing we found was that the age breakdown of places almost entirely explained (~90%) the observed variance in population IFR Image
Read 4 tweets
Health Nerd Profile picture
6 Dec
For those who are interested, the largest clinical trial to date has thus far not shown a benefit for vitamin D supplementation to treat severe COVID-19

medrxiv.org/content/10.110…
That being said, the numbers are still pretty small and I don't think we can make any definite statements either way at this point
That being said, the study looks impressively solid, and this is some truly beautiful honesty wrt sample size
Read 5 tweets
Health Nerd Profile picture
3 Dec
Ugh both the headline and the study it's based on are...pretty dubious

Let's look at some science on twitter 1/n
2/n Paper is here, it's really your bog-standard epidemiological study. The authors took a large database of people who had tested positive to COVID-19 and compared them to people who hadn't in Israel
sciencedirect.com/science/articl…
3/n The two groups were different in loads of ways. However, after putting all the variables into a statistical model, they found that asthma appeared to still be significantly connected to risk of COVID-19!
Read 14 tweets
Health Nerd Profile picture
2 Dec
The important thing to remember is that (outside of a trial) REPORTED side-effects are common. Side-effects LINKED TO THE VACCINE are much less so
Worth clarifying here that what I mean is that there will undoubtedly be many reports of problems that people have following vaccination - this is NORMAL
It's just the law of large numbers at work. If enough people are given a vaccine, sooner or later one of them will be, say, hit by a car shortly after

The question is whether this is related to the vaccine or not!
Read 7 tweets
Health Nerd Profile picture
27 Nov
Wow. Yet another ecological paper on COVID-19 that appears to have some astonishing flaws

Let's do a bit of peer-review on twitter 1/n
2/n Paper is here. Basically, the authors took total COVID-19 mortality in a range of countries by August 31st and correlated them with country-level metrics such as average BMI frontiersin.org/articles/10.33…
3/n The authors found that country-level metrics compiled by the University of Oxford on the stringency of lockdowns did not correlate well with the number of deaths that a country experienced from COVID-19, but other things like BMI and latitude did
Read 18 tweets

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