United States Government COVID-19 Vaccines are defined in the EO as "COVID-19 vaccines developed in the United States or procured by the United States Government"
This does not limit the scope of the EO to those purchased under APAs, but includes vaccines developed here.
That said, implementation of EO will likely start w vaccines purchased by US Govt under APAs. This alone is concerning:
US govt has bought signif. number of global mRNA vaccines:
– Moderna: 100m doses/266m in APAs + 400m option
– Pfizer: 100m doses/590m in APAs + 500m option
US has additional COVID19 vaccine APAs including:
– AstraZeneca/Oxford: 300m doses
– Novavax: 100m doses
– J&J: 100m
Sec 4 of the EO means that international access to these will be only after American demand is met. That plan will be released in next 30 days (Sec 5).
Critically: this EO does not preclude additional executive action by HHS or DoD or other executive agencies under Sec 3(b) to secure access to "COVID-19 vaccines developed in the US" and leaves that door open.
Finally, I am concerned by the use of the term "Americans" rather than "people in America".
Will those of us who are not American citizens get access?
I fear that people who dismiss the impact of so many of these America First EOs forget about the non-citizens who live here.
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Vaccine news that may not be covered outside of Australia:
The University of Queensland/CSL #covid19 vaccine trial has reportedly been abandoned for really interesting reasons, with one less potential vaccine for global COVAX Facility pool.
The UQ/CSL vaccine (V451) uses a molecular clamp vaccine platform with the COVID-19 spike protein: the clamp "locks" the spike protein to be more stable for purification & manufacture. It contains a small component derived from HIV that cannot infect people & poses no health risk
However, this component resulted in some participants (out of 200 volunteers inc. placebo & vaccine) in Phase 1 trial producing "a partial antibody response" which interfered with HIV screening tests (which detect HIV antibodies, not virus) resulting in false positive HIV tests.
This is a huge drop of China #COVID19 documents from @npwcnn. Unfortunately, this leak confirms points I & other China, health, law folks have said since Jan.
I'm going to summarize some of the key findings in 🧵below
Finding 1: Hubei (Wuhan's province) had 20 times increase in "influenza cases" in Dec. High number of "unknown cause" is flag: flu relatively easy to confirm if tested. Also not clear how many confirmed influenza, & if so, if/what samples or GSD was shared w @WHO GISRS.
🧵2/10
Finding 2: signif underreporting of daily new cases & deaths in Feb & Mar. If you recall, this was a live issue at that time w reclassification of case definitions by Chinese health officials, but report indicates deliberate politicization of data to present optimism.
🧵3/10
To follow the article, here's a great explainer thread about our piece by @wormmaps about the science of estimating how many uncounted parasites there may be (including the Brothers Grimm & uncountable things):
Failures in US leadership mean Americans face tough decisions with Festive Season. In Jan, China faced similar choices but w more uncertainty).
A short thread comparing & drawing lessons between:
– January China 🧧Lunar New Year🧧
– November United States 🦃Thanksgiving🦃
1/13
Starting with some case count comparisons between Lunar New Year in China & now in the US:
– 254.3 cases per day: China (Jan 25)
– 135,714.3 cases per day: US (Nov 12)
2/13
Much focus on China's success has been on lockdowns: a time when we didn't know much, didn't have widely available testing & govt support to ensure socio-economic protections. Now, lockdowns can be avoided with strong public health & health systems.
Why did we write this? In light of COVID19, suggestions to reform the mechanism for declaring a public health emergency of international concern (PHEIC) have gained renewed attention & political will. Any substantial reform of PHEICs will likely require amendment to the IHR (2/7)
Already, multiple international and regional processes to review global COVID-19 response, including the operation of the IHR, are underway, including @TheIndPanel, @WHO Health Emergency Program IOAC & the IHR Review Committee.
(3/7)
"The achilles heel of international environmental law... is a lack of enforcement mechanisms, and human rights overcomes [that challenge]" David Boyd #PandemicRecovery@Cambridge_Uni@BennettInst
Dame Barbara Stocking: "What about the next pandemic?"
"We are pressing to have a UN Convention on Pandemics as @WHO does not have the mandate: Member States do not allow it to have an inspector function or doing what is needed to be done" #PandemicRecovery@Cambridge_Uni