That’s an awfully wide confidence interval but early evidence suggests that the Moderna vaccine is effective 14-28 days after the ‘first’ dose. The data on asymptomatic infections is important b/c we don’t know that data for the Pfizer vaccine (they didn’t test for it).
Important note: we don’t know ‘how long’ immunity lasts after a single dose. Hence the need for the 2nd dose until we have more data. (We don’t even really know how long immunity lasts after the 2nd dose. Not for sure.)
tldr; the two mRNA vaccines are well beyond my expectations for efficacy. This is good news, my friends.
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The mRNA vaccines (Pfizer and Moderna) are kind of brilliant at a science level. I’ve had a few people in my real non-Twitter life ask me to explain how it works so I’m going to try my best here in this thread while I’m waiting for a patient to show.
The first thing to know is how your immune system works. Basically, your immune cells attack anything foreign to your body. If it sees a protein or a virus or a bacteria or anything that it doesn’t recognize, it launches an attack.
If it’s fighting off a virus, for example, it takes time to build up a full attack. It’s got to figure out what part of the virus to attack & ramp up production of what it needs to attack those parts. That can take a few days. Meanwhile the virus is replicating and expanding.
Puljujarvi hasn’t knocked it out of the park in his NHL time (though given the context of who he played with, it’s not as bad as people claim).
However, only the Oilers could run a player out of town before he plays a game as a 21 year old.
Let’s take a stroll through Puljujarvi history.
He was drafted as a young 18 year old (May birthday). Despite this, Chiarelli was quoted as saying the Hall trade was easier to make b/c JP was drafted. They thought he’d be ready quickly. His NHLe in his draft year was 20.
I was asked in good faith to expand on this and so I will.
I do think that when so many use mental illness as a scapegoat for violence, we have a tendency to shut down discussions b/c of clear bad faith. However, that prevents us from having honest good faith discussions.
I suspect many people link mass shootings with mental health because for someone to do something so horrible, there must be something 'wrong' with them. They must not be thinking right. They're "messed up" & that becomes synonymous with "mental illness".
So for starters, we should differentiate:
A mental illness should have a clear set of criteria for a specific condition. It's not a catch-all for all acts of deviance or horribleness.
Deep in Ice District, Steve Yzerman sits in an empty room. Before him is a glass if red wine, poured from a bottle of No. 99 Merlot. On a paper plate beside it is a Bobby Nick’s burger.
Jammed in a small adjoining room, connected by a one mirror, sit the entire Oiler management.
Bob Nicholson enters the room.
Nicholson: Steve! Thank you so much for accepting an interview with us!
Nicholson gives a smile and a thumbs up to the men behind the one-way mirror, who all give him a thumbs up back.
Yzerman: Oh, I actually didn’t accept an interview just your offer for lunch. I was just going to fly in to Winnipeg to catch a playoff game but they dropped me off here because apparently Winnipeg doesn’t have an airport. I’ve got a horse and carriage to catch in a couple hours.
Look, I don’t know if Mike Gillis is the answer. But if he wants to walk in the door and snap half of management Thanos style, that might be the most important part of his job.
What happened to Comtois is disturbingly common and it hits a little close to home (or work) for me. Good on him for taking a stand (or at least his representatives) but it may not have turned out that way.
Warning: Meandering thread of indeterminate length ahead