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21 Dec, 23 tweets, 6 min read
I've been tangentially watching this critique by @ikashnitsky of another worrying paper in JAMA Psych, so I thought I'd briefly discuss my own thoughts on the paper in a bit of twitter peer-review 1/n
2/n Paper is here, it looks at suicide rates in Maryland during 2020, and finds that there are racial disparities in these rates. In particular, there were fewer White individuals dying of suicide during lockdown, but more Black people died this way jamanetwork.com/journals/jamap…
3/n @ikashnitsky and one of the authors have had a fantastic back-and-forth, and I strongly recommend you read the threads here:

4/n Now, I am not a suicidologist, and while I have my own experiences of mental health issues it is not my primary area of focus
5/n I'm also a white Jewish guy from London, so at best my insight into racial issues is minimal aside from an academic understanding
6/n That being said, I think it's worthwhile to actually look at what the study found in terms of numbers

The authors essentially looked at the mean rate of suicides in three 2-month time periods (Jan/Feb, Mar/Apr, May/Jun) for different races
7/n Statistically, the choice to use the crude number of daily suicides is very strange. Suicides don't happen every day in this dataset (there are too few), and crude numbers are usually not very useful without a denominator
8/n That being said, this is what the authors found. Suicides decreased by ~20% in Black people in periods 1 and 3 (Jan/Feb+May/Jun) but doubled in period 2 (Mar/Apr), coinciding with the lockdown and COVID-19
9/n In contrast, suicides in the White population increased in period 1, and dropped significantly in periods 2+3 by 25 and 30% respectively
10/n Now, the authors have not standardized these rates to population, but that is fairly easy to do. The population figures for Maryland are here: datausa.io/profile/geo/ma…
11/n So, standardized to population we get these revised numbers

Still interesting, but immediately a bit less enormous in terms of the change
12/n It's interesting at this point to note that the overall suicide rate in Whites in Maryland appears to be 2-3x higher than that of Blacks, which raises the question of age-adjustment and whether it would impact these results
13/n That being said, it is immediately pretty obvious that the overall rates have not changed at all in Maryland over the first 6 months of the year for Black people. The yearly avg noise is bigger than the margin between 2019 and 2020
14/n Conversely, there is clearly a strong decreasing trend for the suicide rate in White people in Maryland, which has gone down by quite a bit every year for the last four
15/n So overall in this time period Black suicides haven't changed, and White suicides have gone down quite a lot per 100k person-years

This doesn't really seem to support the authors conclusion that COVID-19 has caused divergences in the suicide rate by race
16/n If we look at the individual time-periods, the data gets a lot more noisy, and it's very hard to discern an impact. In period 3, for instance, both Black AND White suicides appear to be trending down
17/n In period 2, this is reversed, with White suicides still trending down but Black suicides trending up
18/n Indeed, the exact thing that the authors have attributed to COVID-19 - a doubling in the Black suicide rate - happened in 2017/18 in period 2
19/n Ultimately, the numbers just aren't there to take home much meaning from this in my opinion. Overall, there have been no changes in suicide rates by race in Maryland in the first half of 2020 - the figures show that quite clearly
20/n This is not to say that there should not be targeted efforts to help Black people with mental health, which is of course a priority that cannot be ignored. Public health equity is a really important consideration
21/n And it's also not to say that a study with larger numbers may not be able to show such a difference. It is certainly possible that there is a meaningful change here that is simply not possible to see with so few events
22/n That being said, numerically I think it's important to note that the doubling of suicides in the Black community during Mar/Apr in Maryland was entirely offset by a 20% reduction in suicides in the preceding and following months
23/n There may be a statistical test that shows significance of a sort here, but conceptually I don't think there is much meaning to be garnered from numbers like this

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More from @GidMK

23 Dec
Disagreement over science should not consist of personal attacks

That is not an excuse for uncritically accepting all bad science, nor for refusing to critique things that are clearly flawed
Many people have taken my criticisms of Ioannidis' papers, for example, to be some sort of horrifying vendetta, even though I've never once said anything bad about the man himself
The problem is that some people see any criticism of senior academics by their juniors as impolite and disrespectful, and therefore a personal attack

I find this attitude endlessly absurd
Read 4 tweets
22 Dec
It's coming towards the end of the year, and there are still countless people minimizing the pandemic and spreading untruths

So I thought I'd do a bit of a thread of FACTS about COVID-19 1/n
2/n Fact 1: the death rate of COVID-19 varies substantially by age, but is high even for relatively young people

For example, a 1 in 2,700 risk of death from COVID-19 for a 35 year old, based on our comprehensive paper on the topic link.springer.com/article/10.100…
3/n Fact 2: COVID-19 is MUCH more dangerous than influenza

For younger age groups, COVID-19 may be similarly lethal. For anyone over 30, it is much worse. @zorinaq has a nice graphic on this
Read 34 tweets
21 Dec
Wow, 15 locally-acquired cases in NSW. So 23-30-15

That's a huge relief for Sydney, although we won't know for sure if the outbreak is controlled for a few days yet #covidnsw #nswcovid
For those who made fun of the "gold standard", I'd be interested to know of anywhere in the world that ramped up testing by 8x and went from R(t) ~1.4 to R(t)<~1 in THREE DAYS
38,000 tests in one day. That's 5 tests for every 1,000 people in the state in 24 hours!
Read 5 tweets
17 Dec
The authors of the Great Barrington nonsense have produced a website called "collateral global", claiming to document the collateral effects of COVID-19 lockdowns

I thought I'd have a look at the scholarship on display 1/n
2/n First up - suicide. I have actually looked into this subject a fair bit, and as someone with mental health issues I take a fairly personal interest in the statistics

What does this global repository say?
3/n There are currently 4 studies listed. One found no change in suicide rates, one is an opinion piece by a psychiatrist, and the other two are cross-sectional studies of suicidal ideation
Read 15 tweets
17 Dec
This is a massive step by Twitter. If implemented across the board, it could largely shut down many denialist accounts
Some generic responses for all the people replying:

- Twitter is a private company. They do not owe you the right to their platform to spread misinformation
- This is preventing lies about one, specific thing, you can still lie about other things
- if this makes you want to leave Twitter, it makes no sense to reply to this tweet - deleting your account is a much more logical step
Read 5 tweets
16 Dec
I think that this article by @PeteJamison looks at professor John Ioannidis and his statements during the pandemic, but leaves a few of them out

So I thought I'd just tweet out some things said in papers that prof Ioannidis has written this year 1/n
2/n Note: these are all from published or preprinted research, and I'm directly screenshotting so you can read the words for yourself
3/n Back in May, from the original preprint of the IFR paper
medrxiv.org/content/10.110…
"the worldwide IFR of COVID-19...may be in the same ballpark as...influenza (0.1%, 0.2% in a bad year)"

This was a mistake (the IFR of flu is not 0.1-0.2%) Image
Read 15 tweets

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