Oxygen supply in hospitals is getting a lot of media coverage. Some hospitals are using five times more oxygen than usual triggering low pressure alarms. Media reporting oxygen supplies ‘running out’ and ‘not enough to go round’. The problem is not quite what it sounds… 1/12
We don't usually think about oxygen supply. It isn't something we notice until the oxygen pressure alarms go off. That used to be rare. The unfamiliar and emotive problem can seem frightening for NHS staff and public alike. This from @ChrisCEOHopson 2/12

Oxygen supplies don’t run out like an electricity power cut. Instead the pressure drops like it can with the hot water system in your home. Your shower doesn’t run dry but the water pressure is not what you need. You may need to turn some other taps off to solve this. 3/12
A large hospital with 800 beds would normally use around 1000 litres oxygen per minute may currently be using up to 6000 litres/minute. At these rates the pressure at oxygen outlets in the wards can dip below our strict pressure limits, setting off unfamiliar alarms. 4/12
The reason we are using so much oxygen is because so many of our patients have breathing problems due to COVID-19, causing low blood oxygen levels. In one ward we worked out that 20 patients used a total oxygen flow of 800 litres/minute between them. 5/12
Different oxygen delivery devices, from low flow nasal oxygen to an ICU ventilator, can use anything between 3 and 100 litres of oxygen per minute. A relatively new technique using high-flow nasal oxygen has been invaluable but massively increased our oxygen use. 6/12
There are lots of things we can do to manage the problem. We can be more careful to avoid wasting oxygen, for instance, by turning oxygen taps off whenever the patient isn’t using it, and only giving patients the amount they actually need. 7/12
There's also lots of discussion among doctors about how high blood oxygen targets should be for patients with breathing problems. This is one recent clinical trial (of several) suggesting we could safely give patients less oxygen than we are used to. 8/12
nejm.org/doi/full/10.10…
Most NHS hospitals have created ‘oxygen marshals’ to walk around the wards, turning down oxygen flows where it is safe to do so, and talking to staff about the problem. Most are senior doctors, nurses or physiotherapists. This can reduce demand by more than 10% on its own. 9/12
Hospitals store liquid oxygen in a tank (picture) which gradually evaporates into gas feeding the pressurised piped oxygen supply to the bedside. We are supplementing this by connecting large cylinders of oxygen to the system to support the pressure in high use areas. 10/12
We also have oxygen concentrators which draw in surrounding air (21% oxygen) and remove most of the nitrogen to give enough oxygen for those patients who only need a little extra to help them breathe. 11/12
The real issue with low oxygen pressure is how this highlights just how many patients NHS hospitals are treating for serious breathing problems due to COVID. We have solutions in place and patients should not worry about getting the oxygen they need. 12/12 Photo: @jometsonscott

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More from @rupert_pearse

20 Jan
A bit of controversy at the moment about medical students redeploying in Healthcare Assistant (HCA) roles. Some unfortunate language which I’m sure is regretted. I’m very involved in the @QMULBartsTheLon @QMUL med student redeployment and would like to point a few things out. 1/8
In the first wave (March), med student studies were suspended. Ours had just finished final exams and *volunteered* to join us to support patient care. They did not expect to get paid. They were incredibly professional and made me very proud to be a @QMUL prof. 2/8
In the second wave (January) our students’ studies have NOT been suspended. We (@QMULBartsTheLon) have *sent* them to help. While many would choose this, not all would. Our final years have major exams looming and must also complete educational log books, attend teaching etc. 3/8
Read 8 tweets
19 Jan
Optimistic news: National data on new coronavirus infections data do now show we have passed the peak. Good news but really this is just the end of the beginning for the NHS response. 1/7 https://coronavirus.data.gov.uk/
Firstly, the national data hide regional differences. New infections are still increasing in many parts of the UK. NHS hospitals in different areas will need to support each other for some time to come. 2/7
This map illustrates this much more clearly. Many areas of the country still very badly affected by new infections. This affects NHS healthcare in pretty much every part of the UK. 3/7 https://coronavirus.data.gov.uk/
Read 7 tweets
17 Jan
What reaching the peak means for the NHS: We're increasingly confident we have hit *a* peak and hopefully *the* peak of the second wave of coronavirus infections. Hospital admissions lag behind and will carry on rising for another week or so, but this is still a key moment… 1/10 Photo @jometsonscott
I have talked before about how and why the healthcare the NHS provides right now is simply not as good as usual. We have protected emergency care but routine care for cancer, cardiac disease and so many other illnesses has been badly affected. Especially surgical treatments. 2/10
The surge in COVID patient admissions has a huge impact on other parts of the NHS. We see this pattern often in the winter flu season but it is far worse right now. The shortage of normal hospital beds and ICU beds makes in-patient work very difficult. 3/10
Read 10 tweets
14 Jan
The number of new coronavirus infections may be levelling off, but patient admissions to NHS hospitals for COVID-19 will increase for another 7-10 days. The question of how we choose which patient gets an ICU bed is now a routine one in media interviews. Doctors are worried. 1/11
The burden of decision making around ICU admission traditionally falls on senior ICU doctors. Most of us are privately very worried about what will happen if we run out of resources. The false suggestion that we rationed ICU beds in the first wave has upset a lot of people. 2/11
To be clear, I am not aware of ANY patient who was not admitted to intensive care during the pandemic when the ICU consultants responsible believed that they should be. But we would be failing in our duty if we do not plan for this situation. 3/11
Read 11 tweets
13 Jan
Recent trial results show some promise for Tocilizumab in the treatment of severe COVID-19. Welcome news at a difficult time and excellent work from @remap_cap & @NIHRresearch. But the results raise some difficult issues for doctors treating patients. 1/9
To recap, Tociluzimab is normally used to treat inflammatory arthritis and other immune disorders. The drug suppresses the systemic (whole-body) inflammation (AKA 'cytokine storm') and may reduce the harm of COVID-19 especially for critically ill patients. 2/9
Scientists from @The_MRC population health sciences unit combined data (meta-analysis) from 2107 patients in six trials including @remap_cap. The results suggest a small reduction in 28-day mortality. But most of the benefit was from REMAP-CAP. The results are not clear cut. 3/9
Read 9 tweets
9 Jan
The vaccine conversation took an unexpected turn this week with the decision to prioritise first doses for people who haven't been vaccinated over second doses for those who have. Staff who all year have worked in COVID zones are now preoccupied with their immunity status. 1/8
This has turned out to be a very emotive issue for NHS staff. The topic has split us along invisible fault lines. In some cases, our position in the vaccination queue (and that of people we care about) seems to define our views on the science. 2/8
I'm not expert in the science but listening to those who are, delaying the second dose seems a legitimate thing to debate. Technical discussion revolves around how long the 2nd dose could be delayed and how much difference this might make make, as opposed to a binary debate. 3/8
Read 8 tweets

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