AstraZeneca was signed as Oxford’s partner on 30 April and signed a deal to supply 100m doses to the UK a fortnight later. Ministers were prepared to pay a few hundred million upfront, allowing the company to build its first virus manufacturing process.
The deal was - from the UK government - a demand its citizens be vaccinated first.
“That underpinned all of it,” an industry insider said.
Two sites (Oxford and Keele) were set up to start “brewing” the vaccine. There were early issues but were overcome in 3 months
Bottling takes place in Wrexham....where the suspicious package was.
All credit to getting the manufacturing investment in place early enough to overcome inevitable early teething troubles and produce plenty of vaccine.
A weakness on the EU side is that their proportionate “risk”investment -€1.78 bn (ie with the possibility of no return) seems to be a lot lower that the U.K. (€1.9bn) or the USA (€9bn).
Is the EU’s “risk investment” enough to satisfy their “beat reasonable endeavours” in the contract?
In other words that requirement applies to both AZ and the EU.
Argh! Tweet one!
. “Vaccine manufacturing process” not “virus” manufacturing process.
In graphics: the UK vaccine supply chain | Financial Times
Handy whistle stop tour of the U.K. VACCINE 💉 portfolio and where they are to be manufactured once approved (&, in some instances, the site built) ft.com/content/8b48a8…
According to the NAO £11.7bn has been set aside for the development, manufacturing and purchasing of the vaccines.
4 types of vaccines in the portfolio.
Of those 5 vaccines seem to have performed well in clinical trials.
Of those alone we have reserved 247 million doses.
There should be a lot of “home manufacturing” taking place save for the Pfizer (and maybe the Moderna) vaccines.
That should help secure part of the supply chain.
It should also facilitate manufacture of the vaccine for export purposes.
🦠🦠🦠23,275 new cases. Comparing Mondays by swab date, a decided reduction 👍. Still too high.
⚰️⚰️⚰️1200 (28 day deaths)
⚰️💔⚰️💔⚰️💔 122,118 COVID deaths 😱😱😱
(107,907 ONS/Stats Covid certified deaths to 15/1/21
+
14,211 (28 day deaths)
Both by date of death.
⚰️ In this wave we’ve had 17 consec days with over 1k deaths, 6 over 1.2k deaths & 1 over 1.3k deaths (19/01).
Deaths are still being added to most of these days.
In April there were 23 consecutive days with over 1k death
Peak being 8/4/21 = 1457 deaths
Deaths by date of death
🦠. TESTS. 23,275. See screenshot on the right to compare Mondays (by swab date).
Most of 25/1/21 should have been processed by now so it does look like a real downward trend .
Positivity in England only down to 11.9%. Still v high
I think the paper concerned suggests the subject picked up Covid twice, once in May and once in October. Two different variants with the first incident producing insufficient immune response to prevent the second variant.