1/ The major #covid19 outbreak from @BrighamWomens where I work is now published in @AnnalsofIM — definitely worth a read. Phenomenally detailed work here from many smart people.

The index patient tested negative twice, but soon became positive after.
acpjournals.org/doi/full/10.73…
2/ “The virus was likely introduced into the facility by a symptomatic patient who tested negative twice on admission but in retrospect was contagious from at least hospital day 3 and infected staff and patients for at least a week before detection” #covid19
3/ The infection control team & overall program at our hospital is awesome. They are among the smartest people I know. And despite all of the protective measures in place, transmission & a serious #covid19 cluster still happened.
4/ Among staff cases that responded re their use of personal protective equipment, 23/23 responded that they wore surgical masks at all times; 0/23 reported wearing N95 at all times.
5/ Why? Because we have a universal masking policy for surgical masks + eye protection. And we only wear N95 masks if the patient is on enhanced respiratory precautions. The index case, after two neg tests, despite ongoing symptoms, was removed from these precautions. #covid19
6/ We have had subsequent outbreaks even after this, albeit smaller; it was one of the main reasons why I chose to wear N95s in almost all patient rooms for a time- and had the rest of our medicine team also do that back in December. It’s easy to do- low hanging fruit here.
7/ The authors note that while it was hard to always isolate the circumstances of transmission, there were two definitive cases infected from the patient while wearing surgical masks and eye protection

Read this section. The patient was masked whole time in one, partly in other
8/ So here we now have a case of #covid19 transmission between patient & staff despite both wearing surgical masks; and the staff also wearing eye protection. And as the authors point out, it is exceedingly difficult to isolate this bc usually have many confounding contacts
9/ Now look at the recommendations section.

Surgical masks & eye protection may not provide adequate protection during close encounters esp if patient cannot wear a mask.

Many patients we care for cannot/do not consistently wear masks- if you’ve been on the wards you know this.
10/ I understand that if all parties are wearing surgical masks - which remember are still 3 layers w/ a meltblown layer similar to N95 (cc @larmbrust) that transmission is less likely (although still happened even here).

Now imagine ⬇️
11/ This is a big reason why we been pushing for #BetterMasks — even if these don’t end up being N95s or equivalents although that would be *ideal* for all indoor poorly ventilated crowding where not everyone has a mask on

Those who want better protection deserve access to it
12/ & even before this cluster was published- why have we been pushing for enhanced personal protection despite limited evidence? Bc it’s another low hanging layer of protection that should be easy to achieve at scale, & evidence generation takes valuable time that we don’t have
13/ Conflating the absence of evidence w/ the evidence of absence is a mistake made early on when some said we don’t need community level masking at all bc we lacked definitive data one way or the other. Let’s not do the same w/ #BetterMasks
14/ We know in laboratory settings that better fitted, better filtering masks do better than regular cloth masks. We are in the process of generating more real world data (here it was surgical masks- if N95s were used consistently, could this outbreak have been prevented?)
15/ & we know in the real world, it’s rare that all parties are consistently wearing any type of masks throughout all encounters all the time. Depending on where in the country you live, it’s increasingly unlikely. We need more people to wear any mask + better masks too #covid19
cc @SalomonJA @ArunaSubraman12 @parsonnt @SethAHoffmanMD really interesting paper here from our infection control team

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More from @AbraarKaran

10 Feb
Short Thread
1/ Another must-read piece from Dr. Mike Klompas @BrighamWomens - lead author of the recent #covid19 outbreak study from our hospital in @AnnalsofIM- I've been lucky to call Mike a mentor this year & have learned a lot from him
What is an AGP?
jamanetwork.com/journals/jamas…
2/ "It has become clear that the traditional dichotomy b/w droplet vs aerosol-based transmission is overly simplistic. In practice, people routinely produce a profusion of respiratory particles in a range of sizes that incl both droplets & aerosols as well as particles in b/w"
3/ "Respiratory particles of all sizes can carry virus and all are potentially capable of transmitting infection. The amount of respiratory particles one emits varies by activity. Quiet breathing generates a small but steady flow of aerosols." #covid19
Read 9 tweets
8 Feb
"And there’s another problem: too much filtration becomes unbreathable. “Are you breathing through the material, or are you breathing through the gaps in the material?” Zangmeister says.
2/ "If you’re breathing through the gaps in between the mask and your face, you’re not getting any filtration production at all."

#covid19 #BetterMasks
3/ "In lab settings, Zangmeister and his team have found these areas where air escapes tend to be behind the cheeks, or right above the bridge of the nose, which can look like a droplet exhalation geyser, he says. "
Read 5 tweets
8 Feb
1/ One of the issues w/ public health policy making is the lack of accountability or even full understanding of the effects of those policies. Yesterday was an example of this when #LACounty @lapublichealth @MayorOfLA restricted outdoor TVs from playing the #SuperBowl.
2/ I personally know of multiple unvaccinated friends who decided to gather indoors as a result.

It was 70 degrees & sunny in Los Angeles yesterday.

The state already opened outdoor dining & made people feel like it was 'safe' to do this.

But then- they ban TVs outside.
3/ What they are essentially telling the public is that they aren't responsible enough to do this.

That the government decides how responsible you are, rather than mitigating risk & giving you ways to socialize more safely.

And then they wonder why...
Read 11 tweets
7 Feb
The messaging from #LACounty is ridiculous. On the one hand, they opened up all of these restaurants for outdoor dining & made people feel like things are getting better- but they aren’t allowing outdoor TVs to play the Super Bowl? People are going to meet indoors instead...
2/ This is bad public health. It’s just like when beaches were closed during July 4th. We need to mitigate risk & create safe options for socialization - bc people have shown time & time again that they will socialize either way (not blaming them)
3/ Alternatively they could have set up outdoor viewing sites at parks etc; created distanced pods— many ways to get creative here as was done in other places. But just assuming that people won’t congregate when they have been told it’s getting much safer now...?? #covid19
Read 7 tweets
3 Feb
1/ This story saying that a local health dept has changed their exposure time to any contact without masks ("1 second") doesn't mean that you will get infected in one second- but it does point out that 6 feet/15 min is not a hard/fast rule & never was.

theglobeandmail.com/canada/article…
2/ There are many possibilities for why new variants are "more transmissible"; but in the real world, figuring out the "why" takes time- and we don't have time. We must utilize the best protections we can right now- mitigation of risk is name of the game

3/ With vaccinations, it seems like our attention to other protection measures have fallen to the side- understandably bc there are only so many resources that public health departments have. Doing one often means not doing another (staff, funding etc)
Read 5 tweets
2 Feb
1/ Contrary to some media headlines, our proposal for #BetterMasks has not been to “just give everyone N95s”

If that was, I would be using #N95Masks

I think of masks the same way I think of any risk mitigation. Better is better. Unregulated cloth masks not the bar to settle on
2/ we even specifically asked CNN to change the headline (they initially chose N95 masks) bc the idea behind this movement was always to provide folks w/ a multitude of options- N95s are one of those. But so are high grade surgical masks w/ mask fitters

cnn.com/2021/01/29/opi…
3/ The arguments saying “just get more people to wear any mask”- guess what?

We should do both

& getting “anti-maskers” to wear a mask is actually IMO a harder problem than getting someone who already believes in masks a #BetterMask (which helps them around those who don’t)
Read 11 tweets

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