📍Leadership: Because of growing cases of #B117 & #B1351 variants, Germany 🇩🇪 further extends its #COVID19 lockdown until March 7.
Goal: 🇩🇪 will not lift restrictions until cases down to 35 per 100k per week (~5 per 100k/day)—currently ~68/100k/week. 🧵
2) With an eye to an outbreak of the South African #B1351 variant in the Austrian region of Tyrol bordering Germany's Bavaria state, Merkel said she had conveyed her "concern" to Austrian 🇦🇹 Chancellor Sebastian Kurz on Wednesday.
3) “The text (of guideline) stresses that schools and daycare centres should be "the first to gradually reopen", but that it is for individual states to decide how and when that happens.”
4) Germany will review whether nursery workers and teachers can be given higher priority in vaccinations.
Hairdressers will, however, be able to reopen on March 1st, regardless of the lockdown extension, provided they adhere strictly to hygiene regulations.
5) “We want to do everything in our power so that we don’t end up riding an up-and-down wave of openings and closures,” Merkel said, calling the period until mid-March “existential” for Germany’s management of the pandemic.
6) “But she called on Germans to be patient as fears grow over more contagious virus variants first detected in Britain and South Africa.”
7) “The new strains “are spreading especially quickly and require significant additional efforts”, the government said in conclusions agreed at the meeting.”
8) What are the current rules?
•All nonessential shops & services remain closed.
•People in shops & public transport are required to wear surgical masks or FFP2.
•Employers must, wherever possible, allow employees to work from home until March 15. google.com/amp/s/amp.dw.c…
9) •Contact at private meetings is restricted to just one other person not living in the same household.
•Schools are largely closed and students are taught through distance learning.
10) head of German intensive care association, DIVI, warned that reopening schools and kindergartens would lead to a re-emergence of virus cases.
"Schools and kindergartens are unfortunately places where the virus is passed on," DIVI head Gernot Marx told Rheinische Post.
11) “Germany's national disease control center last week said that the more contagious variant of the virus first observed in Britain has now been seen in most of Germany's 16 states.
Another variant from South Africa #B1351 has also been reported several times in Germany.
12) “Considering the virus mutations, the steps to lift the restrictions must come carefully and gradually in order to avoid risking the successful curbing of infections," the 🇩🇪 document stated.
13) Austria now has over 430 confirmed and suspected cases of the more resistant #B1351 variant. This is worrisome. The other B117 is also rising fast in Germany and Denmark.
14) Meanwhile in Denmark, which sequences all #SARSCoV2 samples from all cases now, the % of #COVID19 now #B117 from 🇬🇧 is up to 27%! Denmark CDC is right to be worried.
15) “Experts tell us that it will be only a matter of time until these mutations will become dominant,” Merkel said in a speech to parliament in Berlin. “We know that the danger of mutations can again wreck our successes.” bloomberg.com/news/articles/…
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We need to call Moderna vaccine by the true proper name of “NIH-Moderna vaccine”. It was mainly developed at Fauci’s NIAID. Moderna honed its mRNA tech via DARPA grants & also didn’t disclose federal support in patents, violating Bayh-Dole Act. HT @mattbc.
2) @mattbc is right in calling out this nonsense by Moderna to hide it got tremendous federal support for the vaccine in its patent. This is a violation of the 1980 Bayh-Dole Act. And @moderna_tx possibly violated it by not disclosing in 154 patent apps. washingtonpost.com/business/2020/…
3) Moderna vaccine works folks. @KizzyPhD from the NIH is famously one of the co inventors of the vaccine. But this doesn’t change that Moderna needs to publicly acknowledge in its patents that its vaccine was taxpayer funded and NIH co developed, akin to Oxford-AstraZeneca.
What is missing from this CDC school reopening priority list? Airborne virus guidance! Like almost nothing in 33 page document on ventilation except 1 paragraph on open the windows, but only if feasible. Ventilation should be #2 behind masks! #COVID19 cdc.gov/coronavirus/20…
2) Notably absent from new CDC guidance was ventilation. In one short paragraph, CDC suggested schools open windows & doors to increase circulation, but said they should not be “if doing so poses a safety risk or a health risk.” #COVID19nytimes.com/2021/02/12/hea…
3) “C.D.C. gives lip service to ventilation in its report, and you have to search to find it,” said @j_g_allen, an expert on building safety at the Harvard T.H. Chan School of Public Health in Boston. “It’s not as prominent as it should be.”
Worrisome—UK 🇬🇧 data shows suddenly higher #COVID19 positivity % in England 🏴 (where #B117 highly dominant) in children ages 5-9, in both boys and girls, sustained each week over 4 consecutive weeks. Ages 0-4 positivity also increasing. Israel 🇮🇱 has also seen kids case trend.
2) As noted by @dgurdasani1, this is all despite these data really underestimating infection in children (as they are based on symptom based testing). And positivity rates appear highest in early year settings (fully open) & primary schools (20% attendance).
3) Dr @dgurdasani1 believe it is related to schools in England 🏴.
“We are now getting reports of people getting reinfected with a new variant—from 🇿🇦 (#B1351)—suggesting people who’ve had prior infection could get infected again.” says Chief Scientist Dr. Soumya Swaminathan. #COVID19
2) This comes on the heels of troubling data I highlighted last week from the placebo group of the Novavax 🇿🇦 trial that that people previously infected and have #COVID19 antibodies (seropositive) has no protection for #B1351 variant reinfection— not even for severe disease!
3) Last month, South Africa’s CDC also warned about likelihood of reinfection risk because of the lower virus neutralization seen by the E484K mutation in the #B1351 variant.
Vaccinations have gone from 900k per day to now over 1.5 million.
I think Biden’s team under @aslavitt46 & @JeffZients@WHCOVIDResponse can push it to 2 million by the end of Feb / early March, and hopefully 3 million a day by mid April.
Moderna says it has 631.5 mil doses of #COVID19 vaccines on order, of which a whopping 613 million are committed to rich countries like 🇺🇸 🇪🇺 🇯🇵 🇨🇦 🇰🇷🇨🇭🇬🇧 🇮🇱—almost none to developing countries. For COVAX, Moderna vaccine not listed among providers. Sad. investors.modernatx.com/news-releases/…
2) Moderna says it has more countries not disclosed. Why? Poor countries likely wouldn’t hide it. The complete absence of Moderna from discounted COVAX vaccine providers shows where its values for humanity are. @moderna_tx — show you care. Donate to COVAX. gavi.org/sites/default/…
3) While most of COVAX vaccines to developing countries are Oxford AstraZeneca vaccines, Pfizer is also among them, even though it has ultra cold chain requirements. Moderna doesn’t need ultra cold storage. So @moderna_tx has no excuse. gavi.org/sites/default/…