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Eric Feigl-Ding Profile picture
@DrEricDing
Feb 19, 2021 • 14 tweets • 5 min read • Read on X
Sudden Kindergarten outbreak—a once small #COVID19 outbreak in an Austrian🇦🇹 kindergarten exploded from 10 cases Monday to suddenly *32 cases* by Wed—20 cases in kids, 12 adults & caregivers.

(Article in German—translation below). HT @hiems_mollis.
noen.at/melk/coronavir… Image
2) “some caregivers complained of symptoms on Saturday. They were then tested positive for SARS-CoV-2 on Saturday, despite negative rapid tests on Friday. Already on Sunday, the parents of the 75 kindergarten children were informed via the kindergarten app "KidsFox".
3) “Since then, all children and caregivers have been quarantined, the kindergarten and, for safety reasons, the afternoon care KiLo, are closed until further notice.”
4) “However, the number of cases could continue to rise. Although there is no obligation to test kindergarten children in cases of suspicion, they are only considered as K1 persons and have to be quarantined, but a large number of parents have so far had their children tested.
5) “From our point of view, the test density is very high. From an epidemiological point of view, this is very good," says District Governor Norbert Haselsteiner.
6) “As at present, however, the positive Covid cases from Loosdorf are also subjected [sequencing], but this lasts ten days. Only then will it be possible to know whether it is a new type of coronavirus.”
7) while cases so far are mild, keep in mind kids can develop #LongCovidKids too. Like this 13 year old.
8) England also seeing #COVID19 positivity of young kids becoming higher than adults every since primary schools started reopening in U.K.
9) we’ve known for a long time the Covid in kids often tracks with schools.
10) Something similar in an Italian village outbreak — 60% of infections were in kids in kindergarten / primary school in that outbreak. It matches the 20 out of 32 cases in this Austrian outbreak so far too.
11) This is not an isolated edge case. We know school reopening lead to rise in cases. We cannot delude ourselves on this!

Don’t be like when some tried to delude ourselves the virus isn’t airborne or that it didn’t spread asymptomatically or that there isn’t reinfections.
13) Don’t get me wrong, I want kids to got back to school. But we need to do it safely. We need ventilation. Clean air. And safe school cafeteria. I talk about school lunch safety here a lot in this thread 🧵.
14) similar outbreak also being reported in Denmark. Very similar to Italy and Israel 🇮🇱 children.
15) there is also data that #B117 is mot only more contagious than common old #SARSCoV2, but the increase from common type is relatively more in kids 0-9 than in adults...

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More from @DrEricDing

Eric Feigl-Ding Profile picture
Feb 21
Woke or biology? There are actually more than the basic “male” XY & “female” XX sexes. Why? Because biology also creates people with single X chromosomes, or extra chromosomes like XXX, XXY, XYY, or XXX+, plus many 🧬genes. 👉All I’m asking is— please be kind to others. Thanks🙏 Image
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2) “The most frequent SCAs include Turner syndrome (45,X), Klinefelter syndrome (47,XXY), Trisomy X syndrome (47,XXX), and Double Y syndrome (47,XYY).”

pmc.ncbi.nlm.nih.gov/articles/PMC10…
3) “The phenotype seen in SCAs is highly variable and may not merely be due to the direct genomic imbalance from altered sex chromosome gene dosage but also due to additive alterations in gene networks and regulatory pathways across the genome as well as individual genetic modifiers.”
Read 5 tweets
Eric Feigl-Ding Profile picture
Feb 16
I'm shocked a lot of doctors don't know about this newer flu antiviral drug called Baloxavir (XOFLUZA)... that shortens your flu illness by 33%, and reduces your viral load by day 2, versus what a placebo takes 5-6 days to achieve. Baloxavir also seems superior to TAMIFLU (oseltamivir) for smashing your viral load on 2 day, achieving what takes Tamiflu 3-4 days. CDC even lists Baloxavir on their website as one of the top 4 drugs that it tracks whether it works against new flu strains (it works)Image
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2) "Baloxavir was associated with significantly more rapid declines in infectious viral load than placebo or oseltamivir (Figure 3A and 3B)."
nejm.org/doi/full/10.10…
3) Adverse events for baloxavir were no different than placebo. in fact theres even hints that it could be lower than Tamiflu.

"Adverse events that were considered to be related to the trial regimen were more common in oseltamivir recipients (8.4%) than in baloxavir recipients (4.4%, P=0.009)"Image
Read 13 tweets
Eric Feigl-Ding Profile picture
Feb 14
⚠️WORST FLU SEASON ever since 2002-2003 when we began to track flu (red, first graph). Worst hit this year are children ages 0-4 and 5-17. ▶️We also have significantly LOWER flu vaccine uptake this year, one of the lowest flu vaccine coverages (red 3rd graph). Indisputable facts. Image
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2) I don't need to tell you that certain US states have vastly lower vaccination rates than others. See map (lighter green, less flu vaccination coverage), and which have higher (darker green)...

If you want to see details and demographics on which state has the LOWEST flu vaccine coverage rates... the data is here.
cdc.gov/fluvaxview/das…Image
3) It’s not just the flu that is going around… Gaines County, TX, where the epicenter of the measles outbreak is, has one of the lowest measles vaccination rates too.
Read 7 tweets
Eric Feigl-Ding Profile picture
Feb 11
INFLUENZA REACHES EPIDEMIC THRESHOLD in New York—Influenza A (Unknown variety) positivity soars (yellow), while hospitalizations stand higher than past 3 years. The rise of unknown subtyping Flu A has led NY to issue new alert to subtype all Flu A immediately for bird flu. Image
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2) This was the reason for the urgency in NY issuing an alert to subtype all hospitalized cases for bird flu if Flu A. See thread below 👇
3) the testing memo seems very aggressive for bird flu.
Read 7 tweets
Eric Feigl-Ding Profile picture
Feb 10
BREAKING—22 States sue to block Trump WH cuts to NIH research grants. Image
2) Attorneys general representing 22 states sued the Trump administration on Monday, asking a federal judge to temporarily block a major policy change by the National Institutes of Health that would substantially limit payments for research overhead

statnews.com/2025/02/10/nih…
3) In the lawsuit, filed in U.S. District Court for the District of MA, the AGs argued that NIH’s abrupt decision to set a 15% cap on payments for indirect costs would cause major harm to institution budgets, jeopardizing basic operations and medical research.
Read 5 tweets
Eric Feigl-Ding Profile picture
Feb 8
💣TORPEDOING MEDICAL RESEARCH—NIH indirect grant funding just got slashed by Trump to 15%. What does this mean for you? Colleges and universities won’t be able to support students, tuition will increase, especially graduate students & researchers who find cures/preventions for cancer, diabetes, heart disease, Alzheimer’s and more. This will not only raise tuition and hurt pipeline of future scientists/doctors, but COMPLETELY DECIMATE MEDICAL & PUBLIC HEALTH RESEARCH. It will also give more power to big pharma to manipulate research agendas and buy out ideas that should remain in the public domain. Ie THE RICH BIOTECH TYCOONS (eg Vivek Ramaswamy) WILL GET RICHER. The lay public will someday only see future drug/tech prices soar as biotech and big pharma control more science and make more money.

Also, Trump’s NIH posted this graphic - but it ignores that most public universities also heavily rely on indirect to subsidize tuition, and train next generation of scientists and medical doctors doing research. (Public colleges can’t compete with wealthier schools who do have endowments, and hence will fall further behind). Public colleges that do medical research will literally fall apart without this mechanism.Image
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2) People don’t seem to get 2 things:

📌Indirect funds college administration and facilities and support services. Academic advising, building operations, new labs and classrooms for students— where does that money come from? If not indirect grants, then it’ll have to come more from ⬆️student tuition.
3) Most universities don’t have billion+ endowments. Most have almost none — so when you slash NIH indirect grant funding to just 15%… it hurts small schools and public colleges the most—smaller places might even go under. Rich school survive, public schools do not.
Read 4 tweets

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