Many thanks @KatyTurNBC @KatyOnMSNBC for hosting me with @carolelee @ashishkjha we spoke about some exciting new on J&J vaccine, likely to be released soon through FDA EUA, although only 3 million doses so far.
A few things: we need to move quickly ahead of the SGTF variants, so having additional doses is a big plus, given we’ll need about 0.5 billion immunizations to fully vaccinate the US population
Also looking at phase 1-2 data, my guess is giving a second dose will give protective immunity equivalent to Moderna and Pfizer-BioNTech and more durable protection, so don’t be too surprised if a 2nd dose is recommended down the line
But even as a single dose vaccine it looks really good. Some clarification on statements less than 50% efficacy in those over 60 required. This may also indicate the need for a 2nd dose down the line.
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1/3: Many thanks @KatyTurNBC for hosting me @KatyOnMSNBC with @ZekeEmanuel @PhilipRucker sharing our concerns about the variants of concern in NY FL CA and the urgency to accelerate our national COVID19 vaccination program.
2/3: we agree it’s disappointing not having J&J doses available now as promised by OpWarpSpeed, so in lieu of that, do we have options. Both Zeke and Mike Osterholm favor delaying 2nd immunizations for the mRNA vaccines and I understand and appreciate their arguments.
3/3: But I’m less enthusiastic, we don’t have data on neutralizing antibodies for single dose immunizations vs the VOCs and the Scottish study mentioned shows inferiority: 2 dose 88% vs 1 dose 57% in older; 85% vs 72% in younger. I prefer to see AZOx out sooner under an EUA
It’s incredible how, not only have I needed to defend scientists these last 14 months, but also science journalists. The assault on science in America in 2020-21 has been unprecedented. My defending science/scientists a new side occupation for me. Links to papers in attached link
In America, much of this coming from two areas: 1) Political extremism on the far right, rising out of Texas where I live and work, of late linking to QAnon and other craziness. 2) Predatory or weaponized health communication from the Putin-led Russian Government.
1/10: Today we are commemorating the loss of 500,000 American lives from #COVID19. Looking forward to the remarks by the POTUS later on today or tonight. How did we get to this awful place?
2/10: From my perspective there are 4 major factors: 1) Unique aspects of SARS CoV2 and COVID19 2) Missed opportunities in our national response 3) Insistence in 2020 to have the states lead 4) White House anti-science disinformation campaign
3/10: Regarding the unique aspect of the virus, for me it was the "Janus Face" of the SARS-2 coronavirus and its ability to replicate in high numbers in mouth, nose, throat. It meant there were 2 groups of individuals: asymptomatic spreaders, and those becoming very sick.
..and they were pretty brazen about it. In 2020, second to deconstructing the Trump White House antiscience disinformation campaign, I worked to downplay the spectacular claims of pharma company press releases, remindIng American audiences they were meant for shareholders, not us
This was a flaw of Op Warp Speed: never adopting a communication strategy. The gap was filled by company press releases making it appear like vaccines appeared like magic without reference to the more than a decade of NIH Wellcome investments in spike protein targeting R&D.
This in turn caused a segment of the public to distrust COVID19 vaccines, something for which I’m still doing damage control
Many thanks @kendisgibson @LindseyReiser for hosting me @MSNBCweekends: Due to our power disruptions, Texas has now fallen to the bottom of % population vaccinated according to NYT Tracker. We need to make up for lost time to get ahead of B.1.1.7 variant
I certainly share POTUS statement that we can get to normalcy by end of 2021, actually I’m even more optimistic, I think by August-Sept if the stars ⭐️ align. The issue is this: the American lives lost between now and then. Maybe a range between 0.5 million to up to 1 million?
The former number is what happens if we get ahead of the variant and move us up quickly to 3 million immunizations per day. The more devastating number is what happens if we screw around and don’t pick up the pace
1/4: Many thanks @NicolleDWallace for hosting me today @DeadlineWH with @MaraGay @DavidJollyFL speaking on sharp declines in life expectancy from #covid especially in Black and Brown communities, I pointed that life expectancy numbers = averages
2/4: but that my read between the lines is that it means losing a generation of African American and Hispanic moms and dads in their 40s 50s 60s parents of teenagers or young adults, young grandparents. I called this “historic decimation”
3/4: I also very much appreciated @MaraGay comments on the stark reality that every African American adult knows someone who has suffered or lost their life from #COVID19. Last year I predicted this and said COVID will go from a public health to homeland security crisis from this