1/ We reviewed Australian medical guidelines:
Some medical decisions are evidence-based, but many are not - and this varies by specialty
E.g., Australian antibiotic guidelines do not state the level of evidence for recommendations (which is often low)
onlinelibrary.wiley.com/doi/full/10.11…
Some medical decisions are evidence-based, but many are not - and this varies by specialty
E.g., Australian antibiotic guidelines do not state the level of evidence for recommendations (which is often low)
onlinelibrary.wiley.com/doi/full/10.11…
2/ Previous reviews of American Infectious Diseases Guidelines found that only 14% of recommendations were based on the highest level of evidence
jamanetwork.com/journals/jamai…
jamanetwork.com/journals/jamai…
3/ One problem with a lack of evidence is that it leads to overtreatment:
Many antibiotic courses are longer than they need to be - sometimes because shorter courses haven't been tested in randomized trials
jamanetwork.com/journals/jamai…
Many antibiotic courses are longer than they need to be - sometimes because shorter courses haven't been tested in randomized trials
jamanetwork.com/journals/jamai…
4/ A related problem is that doctors overprescribe antibiotics because of clinical uncertainty
The study below showed that a sepsis calculator (a more data-driven approach) could reduce prescribing, reduce harms, and reduce hospital costs
onlinelibrary.wiley.com/doi/abs/10.111…
The study below showed that a sepsis calculator (a more data-driven approach) could reduce prescribing, reduce harms, and reduce hospital costs
onlinelibrary.wiley.com/doi/abs/10.111…
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