PSA for those who have registered/about to get COVID-19 vaccine via the Co-WIN app.
It is absolutely essential that those who have had immune suppressants like chemotherapy or during organ transplants, etc should make it known during the inoculation and avoid the #Covaxin jab.
Covaxin and other live attenuated vaccines should be avoided by:
1. HIV, 2. Cancer & chemotherapy, 3. Organ transplants 4. Taking steroids 5. Congenital immune deficiencies including complement deficiencies 6. phagocyte dysfunctions
Contd..
... 7. cell receptor and signal transmission disorders 8. X-linked agammaglobulinemia which leads to antibody production failure 9. variable immune deficiencies 10. severe combined immune deficiency syndrome 11. complete Di George syndrome
Contd...
...
#12. Wiskott-Aldrich syndrome 13. adaptive immune deficiencies including ataxia-telangiectasia
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Q1: Is there a method to hypothesise the efficacy of COVAXIN when no data has been released?
Q2: How is this efficacy enhanced & measured?
Q3: Why can’t COVAXIN be compared with other mRNA vaccines like COVISHIELD (AstraZeneca), ModeRNA and Pfizer?
n1
We know that COVAXIN, also known as BBV152, is based on a tested technology which inactivates or weakens the whole virus, in this case, SARS-CoV-2. NIV isolated the virus strain (NIV-2020-770) of the coronavirus from a COVID-19 patient and sequenced its genome.
n2
The Lancet has NOT endorsed Covaxin. It has just published the phase I data -the preprint (non peer reviewed version) of which was available since last year. Good that @BharatBiotech published this data, but it does not mean it has a been cleared from the safety perspective.
Safety clearance requires testing in many many people of various groups. In this paper, 3 types different vaccines were tested in 100 people each and compared with 75 people of placebo.
In comparison, @pfizer released the data of its vaccine in the briefings with the @US_FDA as below
My analysis of the paper released by #BharatBiotech researchers & the Press Statement by the Drugs Controller General of India (DCGI) on Restricted Emergency approval of 1out of 3 COVID-19 virus vaccine from Bharat Biotech: A thread...
1. PIB "The Phase III efficacy trial was initiated in India in 25,800 volunteers & till date, ~22,500 participants have been vaccinated across the country"
Fact check "A total of 25,800 subjects will be enrolled & randomized in a 1:1 ratio to receive BBV152B vaccine and control"
1. Fact check contd...
A 1:1 ratio means half of 25800 will be enrolled, of which only (almost) 12900 will be given BBV152B vaccine and the other 12900 will be given a placebo, i.e. Phosphate buffered saline PBS with Alum gel (without antigen)
Gynaecologists, Obstetrics & women that have recovered from COVID-19:
(Or keen beaners of Covid-19)
Women, How were your menstrual cycles post COVID-19 recovery? Want to know what may have happened?
Read on... 1/n
So we know that SARS-COV2 affects a lot of organs in the body apart from the respiratory system. They infection is systemic after a point and the virus is found in many areas of the body including the brain, liver, gut, & the reproductive organs. But once the recovery is over..2n
What do we know about the after effects? A lot of people have reported generalised fatigue several weeks (6-7 or more) post recovery. Not just physical but mental fatigue. And that conversation about depression I had with @dhruv_rathee was never so timely. Everything hurts...3n
My latest: In @AltNewsScience, we previously found Arsenicum Album 30 ineffective as a treatment against coronavirus. Subsequently, AYUSH released annexures to claim that homeopathy strengthens immunity. After reviewing, the claim was found unscientific. altnews.in/homeopathic-dr…
Do you remember the claims of boosting immunity by modulating gene expression of the immune cells via pills? All the science of allosteric regulation to alter proinflammatory cytokines & interleukins? We reviewed each of the studies given by @moayush. Homeopathy is still fraud.
That nanotechnology of homeopathy that work on genes?
The discovery of homoeopathy by Hanemann was in 1796. The first experiment in inheritable units, now we call them genes, was not conducted by Gregor Mendel until 1857-1864, nearly 50 years after the discovery of homeopathy..
India’s 'first' indigenous COVID-19 vaccine COVAXIN, developed by @BharatBiotech with @ICMRDELHI & NIV , approved for human clinical trials from the DCGI. The Phase I + II clinical trials to start next month after pre-clinical studies demonstrated safety & immune response. 👏🏼👏🏼👏🏼
Update: The @BharatBiotech vaccine (called covaxin) was developed & tested in collaboration with University of Wisconsin & vaccine company FluGen. It is delivered intranasally & has completed Phase II trials in the USA. Bharat will manufacture clinical lots of the vaccine. 1/3
The new @BharatBiotech vaccine will be based on an influenza virus where gene sequences from SARS-CoV-2 are inserted into M2SR- vaccine platform (M2-ion channel protein Deficient Single Replication). 2/3