1/🧵
🔥PART 2/2 on #PD catheter complications

#NephTwitter #NSMC #medtweetorials #medtwitter #Nephmadness
You see a patient w/ a past history of C-section for poor inflow/outflow 1️⃣ week post laparoscopic PD catheter insertion
📊What are the possible causes of flow problems?
2/

What’s your approach to flow?

1️⃣ Catheter irrigation → 1L of solution (dialysate/saline)
2️⃣ If slow fill → Flush/aspirate with syringe (aseptic technique! 🧤 😷)
3️⃣ If resistance both ways → Likely two-way obstruction

👇 Use an approach to catheter flow problems:
3/

➡️⬅️obstructions due to intraluminal/extraluminal process

👉Fibrin → most common cause of intraluminal obstruction

👉Fibrin → arises with inflammation (e.g. peritonitis)/embedded catheters too!

👉 Diagnose by clinical suspicion (🔎 for fibrin traces in drain bag)
4/

👉Fibrin can also be extraluminal

👉Fibrin in dialysate drain bag may be an early sign of a profibrotic state → fibrin sheath development, see paper by @PD_Perls ncbi.nlm.nih.gov/pmc/articles/P…

👇Fibrin sheath with retrograde contrast spillage (white arrow)
5/

How do you manage fibrin plug?

1️⃣ R/O kinks w/ X-ray
2️⃣ Aspirate & flush catheter w/ heparinized solution
3️⃣Instill fibrinolytic agent in catheter
4️⃣ If unsuccessful, flexible wire under fluoroscopic guidance
5️⃣Surgical exploration as last step

pubmed.ncbi.nlm.nih.gov/20948542/
6/

🗣”The PD catheter is still not working. The patient is clinically stable without concerning labs & will likely get a catheter manipulation done in 1-2 weeks.”

📊Would you switch this patient to hemodialysis?
7/

⚠️Do not reflexively switch to hemodialysis in patients with non-functioning PD catheters. If there is a long wait-time before manipulation, urgent need for clearance &/or minimal residual renal function then consider transition to HD
👇
8/

What about kinks?

⚡️Catheter kinks commonly occur in the pre-peritoneal space in subcutaneous tissue.

⚡️Kinks can be seen on X-ray
🔥Try inverting the image such that 🦴 appears black 👇, most modern catheters have a radio-opaque line that you can see
9/

⚡Follow the shape of the catheter closely as kinks or twists are NOT always very obvious

⚡Significant wrapping of the catheter can also present with a ➡️⬅️way obstructive pattern, especially if the catheter is folded on itself or completely encased 👇
10/

How do you manage Fallopian tube wrap?

⚡️Laparoscopic manipulation recommended

⛔️Never remove catheter suspected of Fallopian tube wrapping without direct visualization; may lead to Fallopian tube avulsion⛔️

@prakashneph has a great summary here:
ncbi.nlm.nih.gov/pmc/articles/P…
11/

What about omental wraps?

🔥Predominantly outflow failure related but can be two-way if severe
🔥Occurs in about 5-15% of PD catheters
🔥Risk reduced when omentopexy done at time of insertion (⚠️See operative video if interested from 0:04-01:00)

12/

How do you diagnose & treat omental wraps?

1️⃣ Clinical history
2️⃣ Get X-ray with catheterograph
3️⃣ If unclear then get CT peritoneogram
4️⃣ If confirmed, get surgical manipulation of catheter

#ICYMI @NephroShah has 👍overview on approach to flow: renalfellow.org/2018/11/20/let…
13/

Conclusion :
📌Two-way obstruction is due to intraluminal or extraluminal causes
📌Fibrin plug is the most common cause of intraluminal obstruction
📌Invert images (black bones) on X-ray to check for catheter kinks
📌Fallopian tube wraps need surgical manipulation
14/

🏁This concludes Part II of catheter complications in PD
Many thanks to @NSMCInternship @captainchloride @amyaimei @drM_sudha & @Nephro_Sparks for the continued support on this #tweetorial!

Stay tuned for regular #PD pearls #Nephtwitter #medtwitter moving forward!

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More from @bourneauguste

4 Mar
1/14
⚡Thread ONE of TWO on troubleshooting PD catheter complications
🗣“Catheter isn’t working, time to switch to hemodialysis”
🗣 “PD catheters can be so frustrating”
Have you heard these 🗣 before?
You are not alone!
#NephTwitter #tweetorial
Got⬇️flow on PD, what's next?
2/14
🔥Maintaining peritoneal access is a lifeline for PD patients

⚡Up to 20% of PD transfers to HD are from catheter complications pubmed.ncbi.nlm.nih.gov/12322816/

⚡Prompt management of catheter complications may prolong patient survival on this modality
3/14

There are 2⃣ types of flow failures:
📌Inflow
📌Outflow

They may occur independently or at the same time ➡️⬅️

In this #tweetorial we will be focusing on the most commonly encountered flow problem in PD, outflow failure
Read 14 tweets

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