Thread by @BadgleyLaurence

ALTERNATE EXPLANATION OF CFS/ME/LONG-COVID: Best studies of physiologic commonalities of these disorders have measured metabolism, genetics, hormones, cytokines, mitochondrial respiration, & etc. The only common phenomenon that correlates with occurrence of these disorder is ....

https://twitter.com/badgleylaurence/status/1370623007937359872

The common thread of CFS/ME/LONG-COVID is the measured intensity of the initial insult; as in days of bedridden status & severe locomotor inactivity. What does this measurement reflect?

Astronauts returning from weightlessness are unable to support their upright musculoskeletal towers. Studies have shown that 2 weeks of strict bedrest result in profound loss of muscle mass and strength.

A body bereft of strength to stand upright becomes beset with widespread muscle spasms in compensatory efforts to support the upright body tower. Widespread muscle spasms generate widespread pain, which induces the organism to seek further bedrest. The process is self-begetting.

A strict sedentary existence exposes the organism to lack of sunlight exposure, nutrient depleted institutional foods, disrupted sleep cycles, attendant CNS dysfunctions, and widespread hormonal dysregulation.

Wasting illnesses of CFS/ME/LONG-COVID might be better studied as to etiology with measurements of SEMG, REM sleep, IGF-1, and Vitamin stores. True healing might occur if peptide precursors of GH, MOTS-c, & other natural dynamic biologicals were rationally employed along with ...

Additional rehabilitation of CFS/ME/LONG-COVID might be possible with musculoskeletal regenerative therapy in warm water, sunlight exposure, and treatment with nutrient dense mostly-proteinaceous foods; coupled with intravenous infusions of key vitamins and minerals.

Let’s not leave out the homeostatic efficacy of Medicinal Cannabis to stimulate appetite, ameliorate pain, induce relaxation and sleep, and to disrupt the hypothalamic-adrenal axis functions that beget anxiety.

@Threadreaderapp unroll