Thread by @_oatc_

@JamesCantorPhD @georgie1801 @jack_turban Once again you do the ultimate transphobe thing of trying to link us to pedophilia. Why does anyone take you seriously, James?

You know your other "reasons" are lies.⬇️

None of that answers why you ignore that seriously inconvenient research.

@JamesCantorPhD @georgie1801 @jack_turban 2 / The Swaab et al research explicitly controlled for the effects of hormones, but besides, it is now known the BSTc is irreversibly gendered in the first months neonatally, & that it is normally due to the effects (or lack of effect) of androgen but at least one known…

@JamesCantorPhD @georgie1801 @jack_turban 3 / …genomic variation can reverse that, yet you still try to use "adult hormone usage" as a fake argument to dismiss the findings.

The research cannot be duplicated only because no one collects the brains of trans people to examine. No doubt MRI scans will soon be able…

@JamesCantorPhD @georgie1801 @jack_turban 4 /…to "duplicate" the results in living subjects

The number of subjects was small (🇳🇱 has a small population so gathering even those, carefully documented samples was a major achievement) but the differences were marked, & included the sole trans guy's sample having a…

@JamesCantorPhD @georgie1801 @jack_turban 5 /… male-pattern BSTc. Publication in @nature speaks to its quality.

@JamesCantorPhD @georgie1801 @jack_turban @nature 6 / The 🐘 in the 🌍 that James et al try to ignore by ignoring BSTc work is the almost universally respected "Organisational & Activational" theory of the function of hormones in the brain neonatally and at puberty in all mammals that it, & trans people's lives fit perfectly

@JamesCantorPhD @georgie1801 @jack_turban @nature 7 / OA theory says hormones (usually androgen) in utero & neonatally, give or take DNA variations, organise some brain & CNS aspects & those of puberty further activate those differences to produce adult behaviour. That offers an explanation for normal pubertal hormones…

@JamesCantorPhD @georgie1801 @jack_turban @nature 8 /… intensifying GI in trans adolescents but bringing congruence in GNC children. Swaab et al had no brains from non-binary subjects but the range of variations of the trans & control BSTcs suggests a continuum that could account for both NB & later-emerging trans people.

@JamesCantorPhD @georgie1801 @jack_turban @nature 9 / Puberty intensifying the GI, followed by life experiences conflicting with their needs then could account for 95%+ of trans people who aren't clear about their GI pre-puberty. All this runs totally counter to Blanchard's 1920s throwback idea that we are either fetishists or…

@JamesCantorPhD @georgie1801 @jack_turban @nature 10/…"gay gone too far". His & Zucker's idea that pre-pubertal trans children are all pre-gay & susceptible to conversion to simply gay cannot be tolerated should those children be irreversibly the most intensely GI with BSTc likely at the far ends of the continuum.

@JamesCantorPhD @georgie1801 @jack_turban @nature 11/ That the difference in size of the BSTc does not appear until the 20s in humans whereas the behavioural effects in some are clear, with most children aware of their gender, in the 2nd year, is explicable by the cell death & clearance of unused neurons being a separate…

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