Good: AstraZeneca vaccine has 79% efficacy in new trial in US, Peru, and Chile. 100% efficacy for severe #COVID19. Good safety profile.

WHAT WOULD HAVE BEEN BETTER: if US approved the vaccine back in Dec 2020, like UK 🇬🇧. Could have saved more lives. nytimes.com/2021/03/22/bus…
2) Dr @VincentRK is right again, we should not have waited for an “American trial” before approving something if clinical trial evidence already showed it was 60-90% efficacious back in December.

Lives have been lost by this “American trial first” approach.
3) AstraZeneca is now FINALLY filing for EUA with the FDA.

It hadn’t done so for all these months yet in the Us!!!
4) Why did AstraZeneca not seek EUA from the FDA back in December? Because they screwed up relationships with the Trump FDA. It was quite a mess—but the science was still sound. But they didn’t get the tacit go ahead to submit for approval. And lives lost. nytimes.com/2020/12/08/bus…
5) Also critical - no blood clot risks found.

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More from @DrEricDing

24 Mar
WOW—25 new cases of #P1 variant suddenly appeared in British Columbia Canada 🇨🇦!! This is the variant from Brazil 🇧🇷 that is utterly decimating the country right now—and had ransacked Manaus 🇧🇷 despite high antibodies levels previously before it hit.

BC 🇨🇦 needs to act fast!!!
3) this is also #P1 in Brazil. Got it @DrBonnieHenry? Please stop #P1 in BC 🇨🇦 ASAP. Image
Read 4 tweets
24 Mar
Let that sink in:

60% of all ICU patients in São Paulo, Brazil 🇧🇷 are now between the ages of 30-50 years old, reports @MattRiversCNN.

Bolsonaro is actively killing the next generation by destroying families. 🧵

Time to call it—“pandemicide”. #COVID19
2) Sobering day - did you know - 1 in 3 deaths from #COVID19 worldwide today—was in Brazil? It’s true.
3) We cannot turn our backs to Brazil. If we lose control of #P1, it will endanger the world. If we let Brazil collapse, it will endanger the world.

The world must act decisively to aid Brazil.
Read 14 tweets
24 Mar
Loud protests erupted across Brazil as COVID-sceptic President Bolsonaro claimed citizens would soon be able to resume “normal lives” despite soaring death toll of 3200+ today.

~1/3 of all #COVID19 deaths worldwide today were in 🇧🇷. 🧵

(HT @tomphillipsin)theguardian.com/world/2021/mar… Image
2) “Bolsonaro, whose anti-science response to coronavirus has drawn international condemnation, made a televised address to the country on Tuesday night, as Brazil suffered by far its heaviest day of losses since the outbreak began last February.”
3) ““What I see before me is a country that attaches no value to the lives of its citizens,” the scientist and broadcaster Átila Iamarino said of his government’s response.
Read 11 tweets
24 Mar
Gigantic boat stuck in the Suez Canal.

It’s been stuck there for hours and blocking all ship traffic both northbound and southbound.

It’s sad but funny too. Photo taken by someone aboard the Maersk Denver ship 🚢 behind #evergiven.

Track it live:
vesselfinder.com/?imo=9811000 ImageImageImage
3) this Suez Canal traffic jam is kinda of a big deal. Image
Read 4 tweets
23 Mar
Devastating record of 3251 new #COVID19 deaths in a single 24 hours were recorded in Brazil 🇧🇷 today. This spike is 40% higher than recent 7 day average. Hospitals overwhelmed. Bolsonaro today also quietly installed his 4th health minister in a year. 🧵 cnnbrasil.com.br/saude/2021/03/… Image
2) Brazil’s population is roughly 2/3 of the US. Thus, if adjusting Brazil’s 3251 deaths today to a US sized population, this would be equivalent to ~4800 deaths if Brazil had US pop.

The state of São Paulo 🇧🇷 also recorded over 1000 deaths today alone. mobile.reuters.com/article/amp/id…
3) Don’t look away. The world needs to face the reality of the crisis facing the people of Brazil, and the crushing effects of the #P1 variant, which is also now circulating worldwide as well as neighboring countries. This could all be us if we don’t collectively act.
Read 9 tweets
23 Mar
THIS IS WILD—the NIH is expressing “concern” about information released by AstraZeneca on initial #COVID19 vaccine trial data. “AstraZeneca may have included outdated information from trial, which may have provided an incomplete view of the efficacy data”
nih.gov/news-events/ne… Image
2) Yeah, NYT picked up on this NIH statement released just **after midnight** (unusual in itself). nytimes.com/2021/03/22/wor…
3) “Companies sponsoring drug or vaccine trials typically wait for the monitoring board to run analyses and conclude that the study has yielded an answer before they announce trial results....”
Read 8 tweets

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