4) Hospitals are so overwhelmed, not only is it almost impossible to find an ICU bed, but hospitals are running out of sedative medications to even perform intubations. Brazil hospitals are now even begging animal hospitals for sedative drugs. Supplies running out in ~1 week.
5) And even then if intubated—80% of intubated #COVID19 patients have died in Brazil in Feb-Dec 2020–the world average is 50%. Mortality % for those intubated also did not improve in Brazil during 2020.
11) as for neutralization of the #P1 variant by vaccines, it’s more evasive of antibodies than #B117 or old strain, but it is neutralized better than the South Africa #B1351 variant.
13) that said, the main vaccine in Brazil is SinoVac, which has 50% overall efficacy and 78% efficacy for severe disease. google.com/amp/s/www.bbc.…
14) but the shortage of vaccine currently is the main crises. Just not enough. Rio De Janeiro is out of vaccines according to CNN. And shipments inbound next month is not enough.
15) Brazil’s crisis is now a threat to global stability - both in pandemic and economically — especially if Brazil destabilizes from this #P1 wave.
18) this is why we must pay attention to Brazil. If we let #P1 variant in Brazil 🇧🇷 become global, it endangers the world. And if Brazil’s economy collapses, it also threatens the world.
Brazil #P1 now invading neighbors: Paraguay Minister of Health “confirms that the Manaus, Brazil variant is already circulating in the country". ICUs in Paraguay are now maxed out—#COVID19 deaths surging.
Let this be a warning—this can all be us.
2) Don’t believe me ICU’s are maxed out? Not only are intensive care beds unavailable anymore, but medical oxygen is now seriously deficient too. All around serious situation. abc.com.py/nacionales/202…
3) Not just Paraguay but also Uruguay deaths are rising quickly.
Shameful—French court rules that sex with 13-year-old girl can’t be tried as rape.
Under 🇫🇷 law, sex with a minor under age 15 is considered illegal only if not consensual. Given difficulty of proving a minor was forcibly coerced, only ~1% convicted. 🤦🏻♂️ washingtonpost.com/world/2021/03/…
2) “France’s top court has rejected a bid to pursue rape charges against a group of firefighters accused of repeatedly raping a girl “Julie” during a period between her 13th-15th birthdays. The men will instead be charged with sexual assault, which carries a lighter sentence.
3) “Attorneys for Julie’s family plan to contest that decision and bring the case to Europe’s Court of Human Rights.
The horrific allegations in Julie’s case have galvanized protesters who want to see France institute stricter age-of-consent laws.
More and more young people. Analysis of data from Brazil found “people aged 30-59 represented about 27% of #COVID19 deaths over the past 3 months or so—7% increase from pre-December numbers.” This matches the trend of many younger adults in ICUs in 🇧🇷. 🧵 cnn.com/2021/03/24/ame…
2) “And amid that (Brazil) surge, a worrying pattern has emerged—more young people seem to be getting severely ill and dying from Covid-19, doctors tell CNN.”
3) Across the country, intensive care physicians keep saying the same thing: In this latest wave, their patients are younger than ever.
"We have otherwise healthy patients that are between 30 and 50-years-old and that is the profile for the majority of patients,"
Keep in mind Florida (the US state with most #P1) has only had 23 cumulative cases in all. BC has had more than that for each of the last 2 days alone.
3) There is debate how fast transmission of #P1 variant is. But several groups estimated it is 2-2.5x more transmissible. The 2.5x estimate is from Brazil research group @obscovid19br....
BREAKING—due to surging #COVID19 cases, India 🇮🇳 has frozen all major exports of AstraZeneca #COVIDVaccine made by Serum Institute of India, world’s biggest vaccine-maker, to meet domestic demand as infections rise. This will also delay supplies to COVAX. reuters.com/article/health…
2) “COVAX has so far received 17.7 million AstraZeneca doses from the SII, of the 60.5 million doses India has shipped in total, and many countries are relying on the programme to immunise their citizens. There have been no vaccine exports from India since Thursday.”
3) “Everything else has taken a backseat, for the time being at least,” said one of the sources. Both sources had direct knowledge of the matter, but declined to be named as the discussions are not public.
First study focused on long-term neurological symptoms in people not sick enough from #COVID19 to need hospitalization: found many visiting neuro clinic had >=4 neurological issues like brain fog, headaches, tingling, muscle pain & dizziness. Avg age 43.🧵 nytimes.com/2021/03/23/hea…
2) “We are seeing people who are really highly, highly functional individuals, used to multitasking all the time and being on top of their game, but, all of a sudden, it’s really a struggle for them,” said Dr. Igor J. Koralnik, chief of neuro-ID and global neurology. #LongCovid
3) “In the study, many experienced symptoms that fluctuated or persisted for months. Most improved over time, but there was wide variation. “Some people after 2 months are 95 percent recovered, while some people after 9 months are only 10 percent recovered,” said Dr. Koralnik.