GREAT NEWS on what we are all eyeing carefully as scientists, public, media: Are hospitalizations per case decreasing in light of vaccines which defang virus . YES, massively. Let's look at statistics from two data sources
healthdata.gov/Health/COVID-1… and
cdc.gov/coronavirus/20…
CASES:
57k cases 7 day average, +7% from prior week
CDC compared to closest 7 day average was July 23, 2020: 63k
Peak of 7 day average 250k cases on January 11, 2021
Currently down -77% from the peak on cases.
TESTS:
1080K tests 7 day average, -10% from prior week July 23, 2020
week 7 day test average was 858K. Test positivity rate was 4.7%; July 23, 2020 positivity rate was 7.3%
Peak of 7 day average was 2.0 million in tests on January 18, 2021
Cases and test positivity: Currently down -46% from the peak on tests. Currently 57k cases vs. 63K July 23
or -10% cases down from there.
Okay, HOSPITALIZATIONS per CASE: New hospital admissions 4.7k 7 day average last week. Hospitalization data not available for the July 23, 2020 time period (only 60% of the hospitals were reporting)
Closest date was August 2, 2020 -- 7 day average
was 5.7 New Hospital Admission a day on 60.8 cases a day. So even though current cases are up +7% (and on +26% of the tests of the closest reporting week) they are not resulting in hospitalizations at the U.S. Total level. Currently hospitalized 33K; peak was 116K on 1/10/21
Deaths: 946: 7 day average vs. 1,031 7 day average week prior or -8.2%.
WHAT ZONES ARE WE IN?
Now, total COVID U.S. hospitalizations are at 5% or in the Light Green Zone. Hospitalizations have been in light green (up to 7% of hospitalizations for COVID-19) since February 24, 2021
Currently, test Positivity Rate is 4.7% (Light Green Zone) and has been in the Light Green Zone since February 27, 2021.
Currently, the total COVID Cases are in the Light Red Zone at 121 per 100k for the last 7 days. (The cases are weighted at a greater threat than
hospitalizations according the the HHS/CDC/ASPR methodology). So, light green zone in hospitalizations and test positivity and definitely falling hospitalizations per case. So don't be afraid to dive deep into data when feeling fear (, it is a lot of work but worth it)
Ok what about Michigan?
Last 7 Day Admissions -- 1,653 vs. prior 7 days 1,039 or +59% -- even with this high % increase -- Michigan stayed in the same "Light Green Zone" for COVID-19 inpatient beds at COVID being 6% of all inpatient beds.
26,271 cases to 1,653 hospital admissions
yields a 6.3% conversion rate case to admission
Prior 7 days 17,707 cases to 1,039 hospital admissions yields a 5.9% conversion rate case to admission. Current COVID-19 impatient beds -- 6% (Light Green Zone) -- Prior 7 days -- 4% (Light Green Zone)
Current COVID-19 ICU beds
-- 12% (Yellow Zone) -- Prior 7 days -- 9% (Yellow Zone). Michigan Ranks #29 in vax for 65+ fully dosed. Although Detroit trails MI according to the Atlantic. Article is 8 days old, but Detroit was trailing
theatlantic.com/health/archive…
in vax by 18-23% depending if looking at 65-74 or 75+, on first doses. "The vaccination of people 65 and older and of nursing-home residents should blunt the death toll of a rise in cases. But according to state data, Michigan has administered first doses to 61 percent of its ..
its residents aged 65–74, and 62 percent of residents 75 and older. Detroit’s figures are much lower: The city has given first doses to only 43 percent of those aged 65–74 and 39 percent of people 75 and older. For comparison, the CDC reports that 66 percent of the U.S.
population aged 65 and up has received at least one dose of vaccine. The numbers are even worse for Black people in Michigan: Statewide, just 28 percent of Black residents 65 and older are known to have received at least one dose of vaccine. Overall, Michigan has administered
first doses to only about a quarter of its total population, and that number falls to 15 percent in Detroit." So maybe what is happening in Michigan is not such a mystery after all? Again, dig deep into hospitalizations per case when putting out our headlines; work but helpful!
Compare to New York: Last 7 Day Admissions -- 3,843 vs. prior 7 days 3,712 or +4% -- even with this % increase -- New York stayed in the same "Yellow Zone" for COVID-19 inpatient beds at COVID being 10% of all inpatient beds. 56,757 cases to 3,843 hospital admissions yields
a 6.8% conversion rate case to admission. Prior 7 days 45,943 cases to 3,712 hospital admissions yields a 8.1% conversion rate case to admission. Current COVID-19 impatient beds -- 10% (Yellow Zone) -- Prior 7 days -- 10% (Yellow Zone)
New York ranks #48 in 65+ fully dosed
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More from @MonicaGandhi9

29 Mar
Another tweet on how hospitalizations for COVID-19 right now are lower than that of influenza in past year due to vaccines. 4 data sources:
1)gis.cdc.gov/grasp/COVIDNet…
2)gis.cdc.gov/GRASP/Fluview/…
3) cdc.gov/flu/about/burd…
4) cdc.gov/coronavirus/20…
As the vaccines take hold, the reduction in 65+ hospitalizations is apparent in COVID. For MMWR Week 11 (w/e 3/20/21) COVID hospitalizations are less than the 2018/2019 and 2017/2018 Flu Seasons in 65+ and less overall than the 2018/2019 Flu Season. Flu The never tested for at
the level of COVID, but, as the data indicates the positivity rates for those who did get a Flu test were much higher than where we are with COVID, now.
Overall
COVID -- 5.7 per 100k -- 382,473 cases on 8,411,837 tests or a 4.1% positivity rate (as reported by the CDC)
Read 6 tweets
29 Mar
Wanted to break down this CDC study today to show you how remarkably effective these vaccines are- simply,
-Without vaccination, you would expect among 1000 people to see 162 infections
-With full vaccination among 1000 people, you would see 1 infection
cdc.gov/mmwr/volumes/7…
This MMWR article looked at data from healthcare personnel, first responders, and other essential and frontline workers across six geographic regions in the U.S. from December 14, 2020–March 13, 2021 since vaccines were being rolled out in these groups early.
In total, this analysis involved 3950 participants (in Arizona, Florida, Minnesota, Oregon, Texas and Utah) who have never had COVID-19 before by laboratory tests 2,479 (62.8%) received both recommended mRNA doses and 477 (12.1%) received only one dose of mRNA vaccine by the time
Read 9 tweets
27 Mar
Why so excited about IgA? Wanted to explain immunoglobulins (antibodies) a bit to explain why the real-world data is showing us that the #covid19 vaccines block transmission. There are 5 different types of immunoglobulins in human body: IgA, IgM, IgG, IgD, IgE. You hear a lot
about "antibodies" and neutralizing antibodies after #covid19 infection & #covid19 vax, which refers to IgG immunoglobulins. But function of IgA antibodies is to protect us at the surfaces that face the world, the "mucosa": nose, mouth, gut, genitals, etc
nature.com/articles/nm1213
Obviously, 1st line of defense against respiratory pathogen like SARS-CoV-2 is where you encounter it (nose/mouth) so IgA responses there after vaccination would help you fight the virus the minute you are exposed and, importantly, limit viral replication so you can't pass it on
Read 13 tweets
26 Mar
Wanted to address "vaccine hesitancy" as supply expands. I truly believe they are safe and profoundly effective but an infection will still go down to low-grade endemicity (very low cases) if many are vaccinated; thereby keeping unvaccinated safe. Vaccinated safe from vax. So, ok
ok if you want to wait & see. I go to same tiny grocery store a lot & person at counter says he is waiting to see others get vaccinated first. That is of course okay. Just like yelling at someone about masks, yelling at someone about getting vax is so wrong. As more sheep turn
pink, nonimmune not as likely to encounter each other & spread. We know these vaccines reduce transmission 80-94% (previous threads, real-world data), so not everyone needs to get vax. Israel case curve below at 56% fully vaccinated; looks like 60% if going to be herd immunity.
Read 5 tweets
25 Mar
Excellent biostatistician @dvgbiostat can help us understand how LOW your risk of getting #covid19 is after vaccination:
-Without vaccination, would expect among 1000 people to see 26 infections
-With full vax among 1000 people, would see 0.5 (or a 50/50 chance of seeing 0 or 1)
Using data from the two healthcare worker studies in NEJM 3/23 DURING surge much exposure (HCW). Also few cases could be asymptomatic and noninfectious. As community prevalence goes down with mass vax, risk vanishingly low.
nejm.org/doi/full/10.10…
nejm.org/doi/full/10.10…
Since papers didn't tell us whether the very low number who got COVID (4/8121) after vax had low viral loads in their nose (or asymptomatic as had asymptomatic screening in one study), likely vaccination controlled symptoms, spread too.
Read 6 tweets
25 Mar
Important to look at dropping hospitalizations in U.S. among older groups getting vaccinated when judging power of the vaccines (as opposed to younger groups not yet vaccinated). So, when you look at crude cases not yet dropping in many places, look at age-based hospitalizations
From CDC source, Look at drop in last 7-day hospital admissions from 2/24/21 to today- rate drop more dramatic in older ages
>65 yrs: Down -44% (17,019 to 9491)
50-63 yr: Down -23% (15,987 to 12207)
18-49 yrs: Down -16% from 2/24/21 (9058 to 7065)
covid.cdc.gov/covid-data-tra…
Greater drop in hospitalizations among older due to >65 being vaccinated first (although 2 doses in majority of >65 not yet reached). In terms of New Jersey, one of the slowest states to vaccinate long-term care facilities which explains lower drop there
Read 5 tweets

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