This list price is more than double the ICER valuation on the CAR. I don’t think the European health authorities are going to green light this CAR at this price. I don’t see Europe paying over $200,000/dose since they don’t care about @NIH fees and/or royalties. $BLUE $BMY
This also highlights a much bigger problem with CARs, esp. for solid tumors. It’s a problem we have always prepared for at SES but could hurt our competitors that plan to charge over $400,000/dose. In solid tumors, if the CARs aren’t curative, they have to be really cheap!
The CARs won’t be curative in solid tumors initially — esp. for the first CARs approved for solid tumors — so companies that think they can charge $400,000+/dose are going to be in for a rude awakening. It’s hard to justify that price tag for next gen CARs. #CARTcells
We’ve been aiming for the goal of $100,000/dose or less at SES. If for some reason we can’t hit that price goal, we will be transparent about why that is, but we continue to plan for disruptively cheap #CARTcells. We are the only US CAR company worried about affordability.
When you are facing a cancer diagnosis, worrying about how to pay for treatment should be the furthest thing from your mind. If you wonder why our competitors hate us, it’s because we care about YOU.
• • •
Missing some Tweet in this thread? You can try to
force a refresh
I am going to add FDA BPCA trial design SME assembly participant to my biosketch. It’s close to being on a working group.
I kept my camera off today as I have wet hair from my shower. I recall Marisa Mayer being criticized for going to a meeting with wet hair, and hence, I kept my camera off. I will ensure I’m camera ready for the next assembly meeting.
Random thought of the day: cosmetic producers for the most part remain clueless when it comes to the environment. Case in point is the new @jaclyncosmetics packaging. If companies don’t start choosing more sustainable packaging, they are going to lose customers IMHO.
I don’t care if your packaging is pretty; the only people who care about that are the YouTube influencers. I do care if your packaging is going to take hundreds of years — if not more — to break down in a landfill.
Large, clunky polymer based compacts are the worst. I am increasingly trying to avoid brands that use this type of packaging.
If @bluebirdbio gets away with a list price that’s double the ICER valuation, does that mean that the Jansen BCMA CAR will cost over $1M/dose once it’s approved by FDA? Paging @RepKatiePorter and her whiteboard. #CARTcells
Diversity and fairness in peer review require non academic peer reviewers. @CSRpeerreview
Women, esp. minority women, report a higher threshold for establishing credibility amongst their peers per Dr. Byrnes. Dr. Byrnes commented that this is sad, and I totally agree.