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Norwegian PURE-3® Profile picture
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31 Mar, 3 tweets, 4 min read
A large soon to be published meta-analysis by Dr Bill Harris (@FariOmega3) et al of 17 prospective studies shows #AllCauseMortality risk was significantly lower among individuals with the highest circulating levels of EPA/DHA #Omega3. #AntiAging #Longevity repository.cam.ac.uk/handle/1810/31… Image
Now out in @NatureComms: "Here, we show significant inverse associations for all mortality endpoints with #Omega3 levels. Hence, chronically higher tissue levels of these FAs operating through a variety of potential mechanisms may slow the aging process." nature.com/articles/s4146…
"In summary, in a global pooled analysis of prospective studies, long chain #Omega3 PUFA levels were inversely associated with risk for death from all causes and from CVD, cancer, and other causes." #AntiAging ImageImage

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Norwegian PURE-3® Profile picture
28 Dec 18
#InflammAging (chronic inflammation) may be the main force driving aging & #Omega3 derived Specialized pro-resolving mediators (#SPMs) have many potential #AntiAging benefits via resolution of inflammation/immunomodulation.
sciencedirect.com/science/articl…
nature.com/articles/s4157…
Systemic cytokines/#NFkB is responsible for aging in skeletal stem/progenitor cells (#SSPC's) but new research shows this aging can be reversed by modulating/decreasing these inflammatory factors
(likely most sustainably with high-dose #Omega3). pnas.org/content/116/14… #AntiAging
Is aging a "self-reinforcing loop" of increased systemic inflammation & oxidative stress already increasing at "middle age"? More & more evidence suggest that it is. #Omega3 may decrease both & be a powerful tool to break this vicious loop. nature.com/articles/s4159… #AntiAging
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