Thread by @fitterhappierAJ

This thread is in regard to the concerning things about Cov2.
I owe the idea to @LgSOS

To start, we have the neuroinvasion seen by @ericsongg @VirusesImmunity et al. rupress.org/jem/article/21…

2/ There is also a predominant symptom of anosmia (loss of sense of smell).

This anosmia is seen as unlikely to be from mucosal/nasal swelling ncbi.nlm.nih.gov/pmc/articles/P…

3/ Interestingly, a few case reports have emerged of Parkinson's following infection.
thelancet.com/journals/laneu…
A worrisome correlate may exist as seen by this preprint: monkeys had precursors of Parkinson's after infection, called Lewy Bodies biorxiv.org/content/10.110…

4/ Loss of smell is an early indicator of Parkinson's, but we cannot draw any associations in relation to cov2.
ncbi.nlm.nih.gov/pmc/articles/P…

5/ Also concerning are the changes in the lungs with Cov2.

In green is collagen- this is the protein that makes nails hard. This is not something you want deposited in your lungs.

nature.com/articles/s4158…

6/ Also, another concerning finding as an immunologist, are the autoantibodies against components of the immune system

Namely those against Interferon gamma

Replete immune signaling is important to prevent severe cov2, and cov2 itself harms signaling 🤯
medrxiv.org/content/10.110…

7/ I will continue to update this 🧵 as more info is revealed.

For now, these are my long-term concerns with the virus beyond the acute phase.