What are your pearls for assessing the mechanism & severity of #mitralregurgitation by #EchoFirst?

#JACCIMG presents an imaging-based curriculum to review functional #mitralvalve regurgitation for #CardioTwitter.

Follow/share this #Tweetorial! (1/15) bit.ly/3gw5MZ2
#JACCIMG Tweetorial Mitral regurgitation (2/15)

Case 1: What is the pathology shown?
JACCIMG #Tweetorial (3/15)

Shown is an example of flail leaflet of the #mitralvalve at the P2 segment.

Surgical #mitralvalve repair is the gold standard; due to prohibitive risk, the patient underwent successful percutaneous repair #TMVR, guided by 3D #EchoFirst.
#JACCIMG Tweetorial Mitral regurgitation (4/15)

Case 2: What is the pathology shown?
#JACCIMG Tweetorial Mitral Regurgitation (5/15)

Shown is mitral annular disjunction (MAD). What findings are associated with MAD? bit.ly/3aAshZ8 #vhdMR
#JACCIMG Tweetorial (6/15)

All of the listed findings (E) are associated with MAD.

Look out for Pickelhaube sign (eg, like a “spike” on a German helmet) – a spike in systolic phase on tissue doppler imaging associated with MAD and leaflet tension. bit.ly/32eU90k
#JACCIMG #Tweetorial Mitral regurgitation (7/15)

Case 3: Does this asymptomatic man with a late systolic click and bileaflet prolapse have severe #mitralregurgitation and require #mitralvalve surgery?
#JACCIMG Tweetorial Mitral regurgitation (8/15)

This patient has late systolic #mitralregurgitation; this typically does not need surgery! Avoid using PISA EROA when #vhdMR is not holosystolic & use regurgitant volume instead. bit.ly/32eU90k
#JACCIMG Tweetorial Mitral regurgitation (9/15)

Biphasic #MR is another pitfall in #vhdMR evaluation & is rarely severe.

Avoid overtracing the jet or turning up doppler gains to make the signal look holosystolic – this may overestimate the PISA bit.ly/2RU0GeR
#JACCIMG Tweetorial Mitral regurgitation (10/15)

Case 4: What is the pathology and what is the optimal therapy: surgical valve replacement, surgical valve repair, transcatheter edge to edge repair (#MitraClip), or medical therapy?
#JACCIMG Tweetorial Mitral regurgitation (11/15)

Shown is a case of Carpentier Type IIIa #mitralregurgitation w/ restricted leaflet motion. Surgical replacement is recommended from high risk of post #MitraClip mitral stenosis due to response to underlying inflammatory disease.
#JACCIMG Tweetorial Mitral regurgitation (12/15)

Case 5: What is the mechanism of #mitralregurgitation in this case?
#JACCIMG Tweetorial Mitral regurgitation (13/15)

Case 5: Functional (secondary) #mitralregurgitation with LV dysfunction is shown. Here are key #EchoFirst clips. What treatment is recommended?
#JACCIMG Tweetorial (14/15)

Case 5: In functional (secondary) MR + LV dysfunction, optimal treatment starts w/ maximal medical therapy, rarely achieved in practice

From #COAPT, #TMVR improved outcomes for secondary MR in LVEF 20-50%, ideally w/ LV end systolic diameter <7cm
#JACCIMG Tweetorial Mitral regurgitation (15/15)

Thank you for following & sharing this #JACCIMG Tweetorial on #vhdMR!

Follow #JACCIMG @JACCJournals and check out the full March 2021 special issue on secondary mitral regurgitation by going here: bit.ly/3tLzcGB

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More from @JACCJournals

8 Apr 20
New #Coronavirus Research For #EPeeps (1/10):
While the use of hydroxychloroquine and azithromycin in patients with #COVID19 remains controversial, many patients receive this therapy. The primary adverse effect is QT prolongation and torsades de pointes/polymorphic VT. #JACCCEP
(2/10): A topical #COVID19 research letter published in #JACCCEP from investigators at @HeartsInRhythm in Vancouver explore the use of a handheld #ECG device versus a standard 12-lead ECG for QT monitoring. bit.ly/34joL10 Image
(3/10) The handheld #ECG would be ideal because it could minimize healthcare worker exposure. The study cohort included 22 patients referred to their center for a possible inherited arrhythmia syndrome. bit.ly/34joL10 #JACCCEP
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12 Oct 19
(1/12) #JACC #Tweetorial: #cvCAD in Young Adults: A Hard Lesson, but a Good Teacher
✔️#AFIJI Cohort 20 year-follow-up: fal.cn/34s2J @ActionCoeur
✔️ Editorial: fal.cn/34s2K by @ErinMichos and @AChoiHeart
@ActionCoeur @ErinMichos @AChoiHeart @MichelZedBay @mathieukerneis @docjohanne @DrHulot_PARCC (2/12) #JACC #Tweetorial: The consequences of premature #cvCAD are devastating. Declines in ASCVD events have not extended to younger adults and rates have increased particularly among women 35-54 yrs old.

Arora, et al @CircAHA: fal.cn/34s2N
@ActionCoeur @ErinMichos @AChoiHeart @MichelZedBay @mathieukerneis @docjohanne @DrHulot_PARCC @CircAHA (3/12) #JACC #Tweetorial: In this issue Collet, JP, et al (@ActionCoeur) describe a cohort of 880 adults who experienced symptomatic #cvCAD at a young age (<45 years) presenting as obstructive CAD followed for up to 20 years. fal.cn/34s3H
Read 12 tweets
11 May 19
(1/10) #JACC #Tweetorial: T2MI is #cvMI due to alterations in either myocardial oxygen supply and/or demand in the absence of acute atherothrombosis. It can occur in pts w/ normal coronaries and in obstructive/non-obstructive stable #cvCAD. fal.cn/AGvR
(2/10) #JACC #Tweetorial: Frequency of T2MI varies widely due to differences in populations, comorbidities, adjudication processes, & cTN assays, w/ a major challenge being the absence of uniform definitions that can be useful w/ high reproducibility. fal.cn/AGvR
(3/10) #JACC #Tweetorial: How T2MI manifests depends on the pathobiology & clinical context, w/ T2MIs less likely to have chest pain, imaging/#ECG abnormalities & ⬇ cardiac troponin concentrations compared to T1MI. Many T2MIs are driven by other illness. fal.cn/AGvR
Read 10 tweets

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