A security guard at the Pan Pacific hotel in #Perth has tested positive, along with two housemates. Short thread with the details.

If you’ve visited any of these sites, you must get tested & quarantine until you receive a negative result.

Masks are mandatory when leaving home.
A hotel quarantine security guard who received their first dose of the Pfizer-BNT vaccine about 1 week ago, worked at the Pan Pacific hotel on the 24th, 25th, and 26th of April.

On the 24th, two international arrivals who would later test positive arrived at the hotel.
The arrivals were from Indonesia and the US. One was infected with a variant common in the US.

The security guard, who developed symptoms on the 29th, is believed to have become infectious on the 27th. He tested positive yesterday, on the 30th of April.
Here are the locations visited in Perth by people who may have been infected.

If you have been at any of the locations below at the times specified, you must get tested and quarantine at home until you receive a negative test result.
healthywa.wa.gov.au/Articles/A_E/C…
Full press conference via @wamnnews:
m.facebook.com/wamnnews/video…
These outbreaks are preventable, and will continue until we take action to prevent airborne transmission.

Here’s what we need to do:

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More from @DrZoeHyde

29 Apr
A good news study of long COVID in 151 Australian children who tested positive for SARS-CoV-2.

12 (8%) had persistent symptoms lasting up to 8 weeks. Cough and fatigue were the most common symptoms.

However, all eventually recovered.
thelancet.com/journals/lanch…
A possible limitation is that mostly young children were studied.

Over half were aged <6 years, and 8 of the 12 children (67%) with long COVID were aged <3 years. As such, it may not be representative of all children.

Other studies have reported a longer duration of symptoms.
However, the proportion of children with long COVID in this study (8%) is consistent with data reported by the Office for National Statistics in the UK.

In the ONS data, 7-8% of children and adolescents reported symptoms lasting at least 12 weeks.
Read 4 tweets
22 Apr
This article contains a number of inaccuracies, @liammannix. The results of the REACT-1 study in England (and many others) are indisputable: children are frequently infected with SARS-CoV-2.

Anyone who says otherwise at this point is either ignorant, or has an agenda.
Furthermore, there is now solid evidence that children transmit the virus at quite similar rates to adults.

At one point in England, children were more likely to bring the virus home than adults, and were more likely to infect their family members.
It’s mathematically impossible to achieve herd immunity without vaccinating children and adolescents.

Children also need to be vaccinated for their own sake. It’s been described as both an “ethical obligation and a practical necessity.”
Read 4 tweets
12 Apr
Study of 25,661 UK healthcare workers (including 8,278 with past COVID-19), showing past infection offers 84% protection against reinfection (93% for symptomatic disease) over 1-7 months. The emergence of the UK variant didn’t make reinfection more likely.
thelancet.com/journals/lance…
During the study, participants had a PCR test every 2 weeks, and an antibody test every 4 weeks, so we can be reasonably sure the majority of cases would have been detected.
There were 1,704 infections in people who hadn’t previously had COVID-19 (of which 17% were asymptomatic), and 2 probable and 153 possible reinfections (1.9%), of which 49% were asymptomatic.
Read 7 tweets
11 Apr
Study of the Pfizer-BNT vaccine in 100 nursing home residents (64 with past COVID-19) & 15 healthcare workers.

A good antibody response was detected in 97% with past COVID-19, 93% of healthcare workers, but only 61% of residents who’d never been infected.
academic.oup.com/cid/advance-ar…
A similar pattern was found with regard to cellular immunity.

A good response was found in 97% of residents with past COVID-19, and in 87% of healthcare workers, but only 48% of residents who’d never been infected.
This study was done 4 weeks after the first vaccine dose.

It’s unclear if the results indicate that older people may take longer to have a good response to the vaccine, or if it is less effective in older people.

If the latter, attaining herd immunity becomes more important.
Read 5 tweets
5 Apr
(1/12) The Brazilian #COVID19 variant is up to 2 times more transmissible, more likely to cause serious illness in young people, and may evade immunity.

Worryingly, it’s starting to spread rapidly in British Columbia, Canada. 🇨🇦

A thread summarising the latest evidence. 🧵
(2/12) Previous research suggested the variant was 40 to 120% more transmissible, and may be able to reinfect people more easily.

Mortality appeared 10 to 80% higher, although it was unclear if this reflected hospitals being overwhelmed with cases.
(3/12) Two new pre-print studies (interpret them carefully) provide more evidence the variant is more virulent.

A study conducted in Brazil’s Amazonas state found that women and young people were more seriously affected once the variant became common.
Read 12 tweets
2 Apr
The California variant (B.1.427/B.1.429), appears more transmissible and possibly more virulent (but less than the UK variant).

Concerning new data suggest vaccine efficacy against symptomatic disease might be reduced (though probably not as much as the South African variant).
However, vaccines have better efficacy against severe disease than mild-to-moderate disease.

It’s therefore likely that efficacy against severe disease will be largely preserved, but we may see reduced protection with regard to transmission.
There is also the potential for reinfections to be more common with this variant, particularly for people who had only very mild COVID-19, and did not develop much in the way of neutralising antibodies.
Read 4 tweets

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