The California variant (B.1.427/B.1.429), appears more transmissible and possibly more virulent (but less than the UK variant).
Concerning new data suggest vaccine efficacy against symptomatic disease might be reduced (though probably not as much as the South African variant).
Concerning new data suggest vaccine efficacy against symptomatic disease might be reduced (though probably not as much as the South African variant).
https://twitter.com/veeslerlab/status/1377735263502229504
However, vaccines have better efficacy against severe disease than mild-to-moderate disease.
It’s therefore likely that efficacy against severe disease will be largely preserved, but we may see reduced protection with regard to transmission.
It’s therefore likely that efficacy against severe disease will be largely preserved, but we may see reduced protection with regard to transmission.
There is also the potential for reinfections to be more common with this variant, particularly for people who had only very mild COVID-19, and did not develop much in the way of neutralising antibodies.
This study provides further evidence that allowing continued transmission provides fertile ground for SARS-CoV-2 to evolve in new and unexpected ways.
Suppression strategies coupled with vaccination programs remain the best defence against COVID-19.
Suppression strategies coupled with vaccination programs remain the best defence against COVID-19.
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