Results of an analysis of adverse events after Sputnik V vax in San Marino. From those vaccinated early, so some healthcare workers & mostly older people. Median age 68, so a much lower rate would be expected than for a general population ...1/n (Preprint) medrxiv.org/content/10.110… 
...Everyone who got vaccinated was invited to participate, but it appears to have had a very low response rate: eg 1,946 out of 8,799 aged 60-89 did (22%): nothing reported to gauge how similar they were to those who didn't. Total group is 2,588, of whom 1,288 had both shots..2/n
...People were contacted 7 days after vaccination, then at 1 month & 3 months. So there would be more recall bias than in a trial with a diary method, but less recall bias at 7 days than for later data...3/n
...Here you can see the impact of age on the reported rate of adverse events: this is after the 2nd shot. The one to look out for here is the light grey bar: none. It's less than 10% for the under 50s but gets as high as 46% in the oldest group...4/n
...Here's the breakdown, incl severity (grade 1 is mild, 2 is moderate, 3 is severe, 4 is serious). This puts Sputnik V vaccine at the higher end of the spectrum for adverse events after Covid vax. (More on this in my next blog post.) Phase 3 trial didn't report these rates 5/5
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