1/ A few #COVID19 vaccine updates for Ontario:

The province will receive 250K doses of AstraZeneca this month, likely reserved for 2nd doses.

Also, it is likely that those who received 1st dose of AZ *may* get a 2nd dose of an mRNA vaccine.

(Photography: Jay Kerr @bombippy)
2/ The push for vaccine equity by pouring vaccines into 114 heavily impacted postal codes was largely successful (to date), with a higher proportion of people receiving a 1st dose in those areas compared to other neighborhoods.

Good news, but the job isn't done.
3/ Pharmacies will massively expand their administration of mRNA vaccines (Pfizer/Moderna) with an aim to have ~2500 online (in all regions) vaccinating by the end of the month.

This will significantly push our vaccination rates higher & help with the rollout.
4/ We need to rapidly include primary care (family doctors & nurse practitioners) in the rollout. There are plans to expand Moderna in primary care settings through May.

Could have been faster, but still a good move - they are experts in counseling, trust, lower barriers, etc.
5/ 2nd doses - see below.

I think there is room to expand this list but if that is the case, we slow down the first-dose-fast approach, and that ends the pandemic faster.
6/ Adolescents/young adults (is that the right word?) aged 12-17 will not be vaccinated until June.

It would be important to get 2nd doses into at-risk individuals (older, immunocompromised) faster.

Hopefully we have enough vaccine to simultaneously cover 2nd doses & youth.

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More from @BogochIsaac

11 May
Ontario is pausing 1st doses of AstraZenca vaccine today as per Dr. David Williams, the Chief Medical Officer of Health,

He cites:
1. Risk of thrombosis
2. Greater supply of mRNA vaccines

Those with 1st dose of AZ will either get a 2nd dose of AZ or perhaps an mRNA vaccine.
They cite the risk of blood clots (aka VITT*) as ~1:60000, based on Ontario data.

*vaccine-induced immune thrombotic thrombocytopenia
The time frame for VITT (blood clots) to develop is between 4-28 days following AstraZeneca.

More on VITT from the Ontario Science Table 👇

Read 5 tweets
6 May
1/ Ontario #COVID19 vaccine update (Take 2 - after twitter hack/drama):

Ontario has vaccinated >130000 people per day May 4, 5 & on track for this today too.

Over 40% of adults in the province have received at least 1 dose.

Some details on past few days & next few weeks 👇
2/ We doled out a ton of AstraZeneca when eligibility dropped from 55 to 40 yrs, but then ⬇️ supply led to ⬇️ pace of AZ vaccination.

Currently there is very little AZ administered this week following recent public discourse.

I am happy for those who received this vaccine.
3/ Equity of vaccine administration was an issue earlier in April. There is ongoing prioritization of supply to heavily impacted neighbourhoods & it's working.

This graph was when 25% of vax supply went to hot spots.

Now hot spots get 50% of supply for the next 2 weeks.
Read 11 tweets
6 May
1/ A few #COVID19 vaccine updates for Ontario:

The pace of vaccination is picking up again.

>130000 vaccines were administered May 4, and >133000 today so far.

>40% of adults in ON have received a 1st dose.

Some thoughts about the past & future weeks👇 Image
2/ People came out in droves for AstraZeneca when the age limit dropped to 40. We had a lot of AZ in the freezer at that time & now there is not much left.

(Much has been said about AZ since then. I am happy for people who received it)
3/ AstraZeneca administered via ~1400 pharmacies & primary care (family doctors & nurse practitioners) pushed our daily vaccine rate to over 130K/day. The pace slowly dropped as supply diminished.

AZ use significantly dropped yesterday & today, likely driven by public discourse.
Read 15 tweets
1 May
1. "Health Minister Patty Hajdu says her government embraces the concept of 'vaccine passports' & will come up with a form of certification to allow vaccinated Canadians to travel internationally."

Smart move & good to be proactive.

bit.ly/3eNTusr by @peterzimonjic
2/ There are a growing number of countries requiring proof of #COVID19 vaccination for travel...18 are currently listed here.

Also the EU just announced they would be open to vaccinated travellers from the USA this summer.

3/ #COVID19 vaccine certification for travel will likely be a global norm:

Read 6 tweets
28 Apr
1/ A few points to clarify a few points...

These vaccines are really really good, but not perfect.

One dose of a vaccine provides excellent protection against #COVID19 infection, but of course 2 doses provide more protection.
2/ NACI outlines protection after 1 dose of a vaccine in their recent document:

"Most importantly, these studies show one dose of the Pfizer-BioNTech & AstraZeneca vaccines are
approximately 80% effective against hospitalization..."

Details: tinyurl.com/saby9kma
3/ Here is some of the data backing up NACI's statement above, but from a clinical trial.

This graph below is with Pfizer...look at how people start to gain protection ~12-14 days after their 1st dose (red line).

Pretty impressive.

Link: bit.ly/3aO00OR
Read 8 tweets
23 Apr
1. Ontario administered >125000 vaccines today.
2. Todays ~125K is not the final count, there are still a couple of hours left.

Yesterday ON vaccinated ~134K (that's 0.91% of ON population in a day).

By comparison, yesterday the USA vaccinated ~3.1 million (0.94% of USA population in a day).

We are catching up.
3. The provinces are all pretty comparable in administering vaccines delivered to them, with a range between 71% to 86% in arms.

Ontario has administered 81% of vaccines delivered to the province. Very much aligned with the others.

Source: bit.ly/3sJCuZA
Read 5 tweets

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