This is an important talk @resiapretorius gave at the @polybioRF Seminar Series. Her early pilot data (~10 subjects) shows that #LongCovid patients have abnormal microclots in their blood samples that are indicative of endothelial + platelet dysfunction:
2/ The microclots in the LongCovid samples contain serum amyloid A, fibrinogen, complement factors, and cytoskeletal kerratin. Dr. Pretorius has already filed a patent for diagnosing #LongCovid using detection of these deposits. She is also writing a paper on her findings.
3/ This is a cool image from her presentation that shows 1) the blood of a patient before #COVID-19 (healthy) 2) microclots in the patient’s #blood during COVID-19 3) microclots in the patient's blood several months later when they had #LongCovid symptoms
4/ A clinician working with Resia is reporting that some of his #LongCovid patients improve on anticoagulant #medications that may break up these microclots. It’s also possible that patients treated w/ anticoagulants during acute #COVID-19 may be less likely to develop LongCovid
5/ We are working on a grant application to see if her team can perform a similar set of experiments in blood collected from patients with #ME/CFS

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