Biotin supplements are commonly used and do not change thyroid function.
On the other hand, biotin often causes lab assay interference mimicking Graves' disease:
⬇️ TSH
⬆️ fT4 and T3
⬆️ TRAb
TRAb is a marker of Graves' disease, the most common cause of thyrotoxicosis/hyperthyroidism, and has a high accuracy :
- Sensitivity: ~ 97%
- Specificity: ~ 99%
📢Beware that despite high reliability, TRAb result can be falsely elevated in the setting of biotin use