Alternate day fasting —every other day you east for 24hrs May work but is not sustainable. I will not be using this #AACE2021#endotwitter
Alternate day modified intermittent fasting (25% caloric intake# one day and 125% following day) maybe better for some secondary measures but not sustainable and conflicting results on if it is better for weight loss #AACE2021#endotwitter
5:2 diet — 2 days eat a very low diet (25-35%) —results conflicting with half showing benefit and half not showing benefit #AACE2021#endotwitter
Meta-analysis of intermittent fasting diets not sig for weight loss but benefit in insulin resistance and maybe hdl/trigs #AACE2021#endotwitter
Never heard of this one—fasting mimicking diet. No comparisons to regular diet but compared to placebo it is beneficial in many parameters in addition to weight incl tumor reduction #AACE2021#endotwitter
Weekly intermittent fasting —one week very low calorie and one week normal calorie. Original study showing good weight loss but overall not a lot of long term data #endotwitter#AACE2021
Here is the one I rec the most —time restricted intermittent fasting (fasting for 14+hrs daily). Benefits proportional to length of fast and doing it 5 days may be as good as 7 days #Endotwitter#AACE2021
But eating later is not better and may actually be worse for cardio metabolic health! #Endotwitter#AACE2021
Glycemic control and glucose tolerance is much better in the morning then later in day. This graph shows results of ogtt performed in morning compared to evening #afternoonDiabetes#Endotwitter#AACE2021
A change (weakened or misalignment) to our circadian rhythm can make it harder to lose weight #obesity#AACE2021#Endotwitter
Bottom line - eating at night (aka “out of sync with circadian rhythm”) is bad bad bad #Endotwitter#AACE2021#obesity
Is skipping breakfast bad? Prob not unless u are also eating a late dinner. Bottom line don’t eat late dinner #AACE2021#Endotwitter#obesity
In dr Peterson study intermittent fasting (time restricted) did not increase energy expenditure but it did increase fat burning and decrease hunger and glu levels #Endotwitter#AACE2021#obesity
Eat your veggies and protein first and leave the carbs for last #Endotwitter#AACE2021
Phenomenal talk by Dr. Courtney Peterson on intermittent fasting and does time of day matter. If you missed it I would recommend going back to watch #AACE2021#Endotwitter
Yes please tell me what to do with the normocalcemic hyperpara's! #aace2021#Endotwitter
In those with primary hyperparathyroidism the majority are asymptomatic. Next highest is kidney stones. It affects the radius more than fem neck more than lumbar spine #AACE2021#Endotwitter#bone
I'm always amazed at the complexity that is obesity and insulin resistance. 2 types: obesity with insulin resistance and obesity w/o insulin resistance both will have mechanical abcd complications but the second will have dysglycemia & the effects from that #aace2021#endotwitter
Obesity exerts multisystemic effects and there is more to it then just weight and BMI -->thus the creation of the ABCD classification using info from EOSS staging system and other data #obesity#aace2021#endotwitter
It's always a pleasure to hear Dr. Biller speak about pituitary topics. Today is on GHD. Bottom line is that there are many barriers to dx & tx esp in those who had dx as kids and are now adults but treatment can come w/ a lot of benefit #AACE2021#Endotwitter
Here are some considerations on who to test for GHD. Highest being those w/ prior pituitary/brain surgery -- if they have 3 or more pituitary deficits then it is more likely they have GHD than not. #AACE2021#Endotwitter#ghd
Characteristics of GH stimulation tests. ITT still gold standard but not very tolerable/safe or speedy. Glucagon cheap, safe but remember the BMI cut off pts. Macimorelin very fast, easy to use and well tolerated but very expensive #AACE2021#Endotwitter#ghd
Intensive behavioral therapy by physicians can be effective helping lose >5% and even up to 10% weight loss #AACE2021#obesity
Using the term "obesity" can have a negative impact on patient care. When speaking with patients, it is better to use the terms "weight" or "BMI" or even "excess weight" #AACE2021#obesity
When to reimage a nonfunctioning pituitary incidentaloma? Risk of growth depends on size. Dr. Molitch recommends <1cm repeat MRI 1, 2, 5yrs. >1cm 0.5, 1, 2, 5yrs #ENDO2021#Endotwitter
What about symptomatic nonfunctioning pituitary adenomas? Depends on surgery outcome #ENDO2021#Endotwitter
What about Acromegaly and Cushings? Depends on treatment and post-operative cure #ENDO2021#Endotwitter