Not every business can be bootstrapped.

For 10 years, this business raised and burned >$2BN with ZERO dollars in revenue.

Then, it became the most important business in the world.

👇🏽👇🏽👇🏽
Today, we released a business breakdown on Moderna

Here are 3 amazing facts about about it:

1) The actual vaccine was developed in less than a WEEK.

Normal vaccines take ~3 years to develop.

The rest of the time pre-release was spent on clinical tests.
2) Moderna purposefully built itself as an mRNA platform vs the “norm” of a single drug therapy.

This platform allows them to quickly code new dna/mRNA sequences via software that within days shows up as a testable physical protein.

This platform approach was key for the vax
Check out the latest Business Breakdown on MODERNA where I host @jrkelly (who is the CEO of ginkgo bio works and an amazing explainer of all things genetics) and Matthew Harrison (who is Morgan Stanley’s top biotech research analyst)

This one is 🤯

joincolossus.com/episodes/56584…

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More from @jspujji

13 Jun
Everyone has only ONE problem.

And it's the same problem.

It's called: The Upper Limit Problem.

Trouble celebrating a big win? When everything is going well, do you wait for "bad stuff"? Then know it

Read this 🧵to to learn abt it, id it and fix it...
Each person has an "inner thermostat" of success/happiness that was set for us as children.

When we exceed our "setting," we unconsciously do things to sabotage ourselves to come back into the familiar/comfortable "temperature."
The classic example: a lotto winner.

It's a proven fact that most lotto winners, regardless of the size of the prize, report similar or LOWER happiness 5-10 years post win.

So much "success" in one area overwhelms their neurosis and they "bring themselves down" in other areas
Read 26 tweets
9 Jun
Sooo… I’m stealth-ishly launching a dtc brand.

Here is how I’m testing on FB ads from zero (with a bootstrapped approach)

Of note… it’s not working, yet!

🧵🧵🧵
First, conceptually there are 5 categories any idea can live in:
1) backlog
2) test
3) validate
4) scale
5) cash cow.

An idea has a full funnel orientation meaning targeting/ad type/creative/price/offer and landing experience.

There are an infinite amt of combos.
There are a ton of levers btw: targeting, creative, messaging, price, offers, landing experience (content, quiz, etc).

That’s why some testing system is important vs throw sh!t against the wall or doing too much too fast.

I prefer to test in series vs parallel.
Read 23 tweets
2 Jun
What do a 77 year old billionaire woman in wisconsin, Facebook ads, Philippines outsourcing, cash conversion cycle, online university leads and @patrick_oshag all have in common?

👇🏽👇🏽👇🏽
They are all part of my most read Twitter threads!

60 days ago I announced @GatewayX and started actively tweeting and since then my Twitter following has gone up by ~5x or nearly 10k followers.

Here’s a countdown of those threads...
6) my favorite metrics for bootstrappers
Read 9 tweets
25 May
100 days ago, I co-founded a business. Totally bootstrapped.

Today, it’s doing $50K in MRR growing 50% per month.

Here’s the story...
I keep a long list of biz ideas that I've come up with over the years. In Jan, I decided to stop trying to find the “perfect” biz.

Instead, I’ll start a few!

If there is a big mkt, a clear value prop, I find the right people and I have an “unfair advantage” I will start it
Worst case, we shut it down. But I want more shots on goal.
Read 25 tweets
20 May
Wow. I just saw the future.

It is getting over a $1BN annual investment with a plan for $100BN+.

And it will change the world.

Here is my summary 👇🏽👇🏽👇🏽
On a plane ride with no internet, I just read @JeffBezos speech “The Purpose of Going to Space” and about @blueorigin

I’m inspired! What a mission...

His POV is beautiful, incredibly compelling and clearly articulated.
Going to space is NOT about finding another planet to live on.

It’s about preserving and augmenting the most amazing planet we know: EARTH.

“Earth is heaven.”
Read 18 tweets
13 May
In honor of the 13th a month, here are 13 of my personal (mostly original) learnings on starting and growing successful companies since 2009... 👇👇👇
1) Tenacity is the most important trait for building a company. It is not intelligence, creativity or salesmanship, but sheer determination.

Wake up every day and push the ball forward.
2) Making decisions is hard; but a ‘bad decision’ outweighs no decision every time.

As you learn, you will even start to make good decisions.
Read 14 tweets

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